A review about design, manufacture, and mechanobiology of biodegradable scaffolds for
bone tissue engineering is given. First, fundamental aspects about bone tissue engineering …

Objective To determine the potential of an integrated, image-based computer-aided design
(CAD) and 3-dimensional (3D) printing approach to engineer scaffolds for head and neck …

The primary thrust of tissue engineering is the clinical translation of scaffolds and/or
biologics to reconstruct tissue defects. Despite this thrust, clinical translation of tissue …

Bone scaffolds for tissue regeneration require an optimal trade-off between biological and
mechanical criteria. Optimal designs may be obtained using topology optimization …

The hierarchical topology optimization model for multiscale design of structures addresses
the problem of finding optimal material distributions at different but interconnected structural …

Recently, as an alternative to metal spinal fusion cages, 3D printed bioresorbable materials
have been explored; however, the static and fatigue properties of these novel cages are not …

In recent years, much attention has been directed to the study of ultralight periodic cellular
materials, such as the so called Periodic Truss Materials (PTMs), which are made up of truss …

A porous material can be designed to promote tissue regeneration as well as satisfy
mechanical and biological requirements. The porous microarchitecture can be specifically …

This work presents a design approach to obtain a cage to enhance the fusion between
adjacent vertebrae of the cervical spine. This approach makes use of a multiscale model for …

Topology optimization has been regarded as a most promising approach in the conceptual
stage of structural design. It has experienced rapid development over the past two decades …