A copy number variation map of the human genome
A major contribution to the genome variability among individuals comes from deletions and
duplications—collectively termed copy number variations (CNVs)—which alter the diploid …
duplications—collectively termed copy number variations (CNVs)—which alter the diploid …
The molecular genetic architecture of attention deficit hyperactivity disorder
Attention deficit hyperactivity disorder (ADHD) is a common childhood behavioral condition
which affects 2–10% of school age children worldwide. Although the underlying molecular …
which affects 2–10% of school age children worldwide. Although the underlying molecular …
Etiologies of ADHD.
RA Barkley - 2015 - psycnet.apa.org
It should be evident from the research reviewed here that neurological and genetic factors
make a substantial contribution to symptoms of ADHD and the occurrence of the disorder. A …
make a substantial contribution to symptoms of ADHD and the occurrence of the disorder. A …
Clinically relevant copy number variations detected in cerebral palsy
M Oskoui, MJ Gazzellone… - Nature …, 2015 - nature.com
Cerebral palsy (CP) represents a group of non-progressive clinically heterogeneous
disorders that are characterized by motor impairment and early age of onset, frequently …
disorders that are characterized by motor impairment and early age of onset, frequently …
Schizophrenia genetics: emerging themes for a complex disorder
DH Kavanagh, KE Tansey, MC O'Donovan… - Molecular …, 2015 - nature.com
After two decades of frustration, genetic studies of schizophrenia have entered an era of
spectacular success. Advances in genotyping technologies and high throughput …
spectacular success. Advances in genotyping technologies and high throughput …
Burden analysis of rare microdeletions suggests a strong impact of neurodevelopmental genes in genetic generalised epilepsies
Genetic generalised epilepsy (GGE) is the most common form of genetic epilepsy,
accounting for 20% of all epilepsies. Genomic copy number variations (CNVs) constitute …
accounting for 20% of all epilepsies. Genomic copy number variations (CNVs) constitute …
Modeling a model: Mouse genetics, 22q11. 2 Deletion Syndrome, and disorders of cortical circuit development
DW Meechan, TM Maynard, ES Tucker… - Progress in …, 2015 - Elsevier
Understanding the developmental etiology of autistic spectrum disorders, attention
deficit/hyperactivity disorder and schizophrenia remains a major challenge for establishing …
deficit/hyperactivity disorder and schizophrenia remains a major challenge for establishing …
[PDF][PDF] GRM7 regulates embryonic neurogenesis via CREB and YAP
W Xia, YL Liu, J Jiao - Stem cell reports, 2015 - cell.com
Summary Metabotropic glutamate receptor 7 (GRM7) has recently been identified to be
associated with brain developmental defects, such as attention deficit hyperactivity disorder …
associated with brain developmental defects, such as attention deficit hyperactivity disorder …
Unmet needs in paediatric psychopharmacology: present scenario and future perspectives
Paediatric psychopharmacology holds great promise in two equally important areas of
enormous biomedical and social impact, namely the treatment of behavioural abnormalities …
enormous biomedical and social impact, namely the treatment of behavioural abnormalities …
[HTML][HTML] ADHD & pharmacotherapy: past, present and future: a review of the changing landscape of drug therapy for attention deficit hyperactivity disorder
JJ Connolly, JT Glessner, J Elia… - … innovation & regulatory …, 2015 - ncbi.nlm.nih.gov
Attention deficit hyperactivity disorder (ADHD) is the most common neurobiological disorder
in children, with a prevalence of~ 6–7% 1, 2 that has remained stable for decades 2. The …
in children, with a prevalence of~ 6–7% 1, 2 that has remained stable for decades 2. The …