Brown adipose tissue and novel therapeutic approaches to treat metabolic disorders

S Roman, A Agil, M Peran, E Alvaro-Galue… - Translational …, 2015 - Elsevier
In humans, 2 functionally different types of adipose tissue coexist: white adipose tissue
(WAT) and brown adipose tissue (BAT). WAT is involved in energy storage, whereas BAT is …

Sarcolipin is a novel regulator of muscle metabolism and obesity

SK Maurya, M Periasamy - Pharmacological research, 2015 - Elsevier
Obesity is increasing at an alarming rate, both in adults and adolescents, across the globe
due to increased consumption of caloric rich diet. Obesity and its associated complications …

[HTML][HTML] Sarcolipin is a key determinant of the basal metabolic rate, and its overexpression enhances energy expenditure and resistance against diet-induced obesity

SK Maurya, NC Bal, DH Sopariwala, M Pant… - Journal of Biological …, 2015 - ASBMB
Sarcolipin (SLN) is a novel regulator of sarcoplasmic reticulum Ca 2+ ATPase (SERCA) in
muscle. SLN binding to SERCA uncouples Ca 2+ transport from ATP hydrolysis. By this …

A Cistanches Herba Fraction/β‐Sitosterol Causes a Redox‐Sensitive Induction of Mitochondrial Uncoupling and Activation of Adenosine Monophosphate‐Dependent Protein …

HS Wong, J Chen, PK Leong, HY Leung… - Evidence‐Based …, 2015 - Wiley Online Library
Previous studies have demonstrated that HCF1, a semipurified fraction of Cistanches Herba,
causes weight reduction in normal diet‐and high fat diet‐fed mice. The weight reduction was …

[HTML][HTML] Fueling up skeletal muscle to reduce obesity: a TrkB story

JY Youn, H Cai - Chemistry & biology, 2015 - cell.com
Targeting TrkB signaling could represent a good therapeutic strategy to prevent obesity. In
this issue of Chemistry & Biology, Chan et al. report the efficacy of 7, 8-DHT, a TrkB agonist …

[图书][B] Differential skeletal muscle energy expenditure in lean vs. obesity-prone rats

CK Gavini - 2015 - search.proquest.com
Obesity, along with is related innumerable health problems, is increasing worldwide,
decreasing quality of life and increasing mortality. Particularly in the US, it is increasing …

[引用][C] Hoi Shan Wong, Jihang Chen, Pou Kuan Leong, Hoi Yan Leung

WM Chan, KM Ko - 2015