Purpose To review the impact of collaborative studies on advances in the biology and
treatment of acute lymphoblastic leukemia (ALL) in children and adolescents. Methods A …

Acute lymphoblastic leukemia (ALL) is the commonest childhood tumor and remains a
leading cause of cancer death in the young. In the last decade, microarray and sequencing …

Acute lymphoblastic leukaemia (ALL) is the commonest childhood cancer and an important
cause of morbidity from haematological malignancies in adults. In the past several years, we …

B-lymphocyte development in the bone marrow is controlled by the coordinated action of
transcription factors creating regulatory networks ensuring activation of the B-lymphoid …

Treatment of acute lymphoblastic leukemia (ALL) continues to advance, as evidenced by the
improved risk stratification of patients and development of newer treatment options …

The added value of IKZF1 gene deletion (IKZF1 del) as a stratifying criterion in B-cell
precursor acute lymphoblastic leukemia (BCP-ALL) is still debated. We performed a …

Acute lymphoblastic leukemia (ALL), the most common malignancy of childhood, is a
genetically complex entity that remains a major cause of childhood cancer‐related mortality …

Patients with pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL) with the
BCR-ABL1 fusion gene form a small, high-risk group with a poor prognosis. 1 Approximately …

CR: complete response; SCT: stem cell transplantation. aRemaining BCP-ALL group
contains eight cases with high-hyperdiploidy (50-62 chromosomes), three TCF3-PBX1 …

Objectives This session of the 2013 Society of Hematopathology/European Association for
Haematopathology Workshop was dedicated to B-acute lymphoblastic leukemia (B …