On the positive and negative affective responses to cocaine and their relation to drug self-administration in rats

A Ettenberg, V Fomenko, K Kaganovsky, K Shelton… - …, 2015 - Springer
Rationale Acute cocaine administration produces an initial rewarding state followed by a
dysphoric/anxiogenic “crash.” Objective The objective of this study was to determine whether …

Multiple Properties of Drug-Paired Cues May Precipitate Reinstatement

MR Castino, SYS Khoo - Journal of Neuroscience, 2015 - Soc Neuroscience
Reactivity to drug-paired cues is associated with increased severity of addiction and
propensity to relapse (Jasinska et al., 2014). Consequently, animal models of addiction …