[HTML][HTML] β-adrenergic receptor signaling in prostate cancer
Enhanced sympathetic signaling, often associated with obesity and chronic stress, is
increasingly acknowledged as a contributor to cancer aggressiveness. In prostate cancer …
increasingly acknowledged as a contributor to cancer aggressiveness. In prostate cancer …
[HTML][HTML] Housing temperature-induced stress drives therapeutic resistance in murine tumour models through β2-adrenergic receptor activation
JWL Eng, CB Reed, KM Kokolus, R Pitoniak… - Nature …, 2015 - nature.com
Cancer research relies heavily on murine models for evaluating the anti-tumour efficacy of
therapies. Here we show that the sensitivity of several pancreatic tumour models to cytotoxic …
therapies. Here we show that the sensitivity of several pancreatic tumour models to cytotoxic …
Infantile hemangiomas, retinopathy of prematurity and cancer: a common pathogenetic role of the β‐adrenergic system
L Filippi, M Dal Monte, G Casini… - Medicinal research …, 2015 - Wiley Online Library
The serendipitous demonstration that the nonselective β‐adrenergic receptor (β‐AR)
antagonist propranolol promotes the regression of infantile hemangiomas (IHs) aroused …
antagonist propranolol promotes the regression of infantile hemangiomas (IHs) aroused …
[HTML][HTML] Antiproliferative effects of β-blockers on human colorectal cancer cells
M Coelho, M Moz, G Correia, A Teixeira… - Oncology …, 2015 - spandidos-publications.com
Colon cancer is the fourth and third most common cancer, respectively in men and women
worldwide and its incidence is on the increase. Stress response has been associated with …
worldwide and its incidence is on the increase. Stress response has been associated with …
Housing temperature–induced stress is suppressing murine graft-versus-host disease through β2-adrenergic receptor signaling
Graft-versus-host disease (GVHD) is the major complication of allogeneic hematopoietic cell
transplantation, a potentially curative therapy for hematologic diseases. It has long been …
transplantation, a potentially curative therapy for hematologic diseases. It has long been …
Stress, metabolism and cancer: integrated pathways contributing to immune suppression
EA Repasky, J Eng, BL Hylander - The Cancer Journal, 2015 - journals.lww.com
The potential for immune cells to control cancers has been recognized for many decades,
but only recently has real excitement begun to spread through the oncology community …
but only recently has real excitement begun to spread through the oncology community …
[HTML][HTML] Neural regulation of pancreatic cancer: a novel target for intervention
The tumor microenvironment is known to play a pivotal role in driving cancer progression
and governing response to therapy. This is of significance in pancreatic cancer where the …
and governing response to therapy. This is of significance in pancreatic cancer where the …
Curcumin pretreatment mediates antidiabetogenesis via functional regulation of adrenergic receptor subtypes in the pancreas of multiple low-dose streptozotocin …
Lifestyle modification pivoting on nutritional management holds tremendous potential to
meet the challenge of management of diabetes. The current study hypothesizes that regular …
meet the challenge of management of diabetes. The current study hypothesizes that regular …
[HTML][HTML] Standard sub-thermoneutral caging temperature influences radiosensitivity of hematopoietic stem and progenitor cells
BJ Povinelli, KM Kokolus, JWL Eng, CW Dougher… - PLoS …, 2015 - journals.plos.org
The production of new blood cells relies on a hierarchical network of hematopoietic stem
and progenitor cells (HSPCs). To maintain lifelong hematopoiesis, HSPCs must be …
and progenitor cells (HSPCs). To maintain lifelong hematopoiesis, HSPCs must be …
[HTML][HTML] Beta adrenergic signaling: a targetable regulator of angiosarcoma and hemangiosarcoma
EB Dickerson, BA Bryan - Veterinary Sciences, 2015 - mdpi.com
Human angiosarcomas and canine hemangiosarcomas are highly aggressive cancers
thought to arise from cells of vascular origin. The pathological features, morphological …
thought to arise from cells of vascular origin. The pathological features, morphological …