Capsaicin may have important potential for promoting vascular and metabolic health

MF McCarty, JJ DiNicolantonio, JH O'Keefe - Open Heart, 2015 - openheart.bmj.com
Capsaicin, the phytochemical responsible for the spiciness of peppers, has the potential to
modulate metabolism via activation of transient receptor potential vanilloid 1 (TRPV1) …

Activation and recruitment of brown adipose tissue as anti-obesity regimens in humans

T Yoneshiro, M Saito - Annals of medicine, 2015 - Taylor & Francis
Brown adipose tissue (BAT) is the site of sympathetically activated adaptive thermogenesis
during cold exposure and after hyperphagia, thereby controlling whole-body energy …

Structural mechanism underlying capsaicin binding and activation of the TRPV1 ion channel

F Yang, X Xiao, W Cheng, W Yang, P Yu… - Nature chemical …, 2015 - nature.com
Capsaicin bestows spiciness by activating TRPV1 channel with exquisite potency and
selectivity. Although a capsaicin-bound channel structure was previously resolved by cryo …

Gender differences in the influence of personality traits on spicy food liking and intake

NK Byrnes, JE Hayes - Food quality and preference, 2015 - Elsevier
It has been proposed, and only minimally explored, that personality factors may play a role
in determining an individual's sensitivity to and preference for capsaicin containing foods …

Capsaicin and related food ingredients reducing body fat through the activation of TRP and brown fat thermogenesis

M Saito - Advances in Food and Nutrition Research, 2015 - Elsevier
Brown adipose tissue (BAT) is a site of sympathetically activated adaptive nonshivering
thermogenesis, thereby being involved in the regulation of energy balance and body …

Physiology and relevance of human adaptive thermogenesis response

FS Celi, TN Le, B Ni - Trends in Endocrinology & Metabolism, 2015 - cell.com
In homoeothermic organisms, the preservation of core temperature represents a primal
function, and its costs in terms of energy expenditure can be considerable. In modern …

Kaempferia parviflora extract increases whole-body energy expenditure in humans: roles of brown adipose tissue

M Matsushita, T Yoneshiro, S Aita, T Kamiya… - Journal of Nutritional …, 2015 - jstage.jst.go.jp
Kaempferia parviflora extract (KP) has been reported to have a preventive effect on obesity
in mice, probably by increasing energy expenditure (EE). The aims of the current study were …

TRPV1 channels and gastric vagal afferent signalling in lean and high fat diet induced obese mice

SJ Kentish, CL Frisby, S Kritas, H Li, G Hatzinikolas… - PLoS …, 2015 - journals.plos.org
Aim Within the gastrointestinal tract vagal afferents play a role in control of food intake and
satiety signalling. Activation of mechanosensitive gastric vagal afferents induces satiety …

Effects of culinary spices and psychological stress on postprandial lipemia and lipase activity: results of a randomized crossover study and in vitro experiments

CE McCrea, SG West, PM Kris-Etherton… - Journal of translational …, 2015 - Springer
Background Data suggest that culinary spices are a potent, low-calorie modality for
improving physiological responses to high fat meals. In a pilot study (N= 6 healthy adults) …

Brown and beige fat: the metabolic function, induction, and therapeutic potential

S Qian, H Huang, Q Tang - Frontiers of medicine, 2015 - Springer
Adipose tissue is an important organ for energy homeostasis. White adipose tissue stores
energy in the form of triglycerides, whereas brown adipocytes and recently identified beige …