Nutrient-sensing mechanisms and pathways

A Efeyan, WC Comb, DM Sabatini - Nature, 2015 - nature.com
The ability to sense and respond to fluctuations in environmental nutrient levels is a requisite
for life. Nutrient scarcity is a selective pressure that has shaped the evolution of most cellular …

Intestinal triacylglycerol synthesis in fat absorption and systemic energy metabolism

CLE Yen, DW Nelson, MI Yen - Journal of lipid research, 2015 - ASBMB
The intestine plays a prominent role in the biosynthesis of triacylglycerol (triglyceride; TAG).
Digested dietary TAG is repackaged in the intestine to form the hydrophobic core of …

[HTML][HTML] Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma

A Nath, I Li, LR Roberts, C Chan - Scientific reports, 2015 - nature.com
Hepatocellular carcinoma (HCC) is the second-leading cause of cancer-related death
worldwide and the factors influencing HCC progression are poorly understood. Here we …

Regulation of AMPK activation by CD36 links fatty acid uptake to β-oxidation

D Samovski, J Sun, T Pietka, RW Gross, RH Eckel… - Diabetes, 2015 - Am Diabetes Assoc
Increases in muscle energy needs activate AMPK and induce sarcolemmal recruitment of
the fatty acid (FA) translocase CD36. The resulting rises in FA uptake and FA oxidation are …

The Arp2/3 complex has essential roles in vesicle trafficking and transcytosis in the mammalian small intestine

K Zhou, KD Sumigray, T Lechler - Molecular biology of the cell, 2015 - Am Soc Cell Biol
The Arp2/3 complex is the only known nucleator of branched F-actin filaments. Work in
cultured cells has established a wide array of functions for this complex in controlling cell …

[HTML][HTML] Dietary lipids inform the gut and brain about meal arrival via CD36-mediated signal transduction

S Sundaresan, NA Abumrad - The Journal of nutrition, 2015 - Elsevier
Sensing mechanisms for nutrients, in particular dietary fat, operate in the mouth, brain, and
gastrointestinal tract and play a key role in regulating feeding behavior and energy balance …

Expression of CD36 by olfactory receptor cells and its abundance on the epithelial surface in mice

S Lee, A Eguchi, S Tsuzuki, S Matsumura, K Inoue… - PLoS …, 2015 - journals.plos.org
CD36 is a transmembrane protein that is involved in the recognition of certain amphiphilic
molecules such as polar lipids in various tissues and body fluids. So far, CD36 homologues …

鸭CD36 基因多态与血清生化指标及肉质的关联分析

李万贵, 王单单, 潘兰兵, 张依裕 - 中国畜牧杂志, 2015 - cqvip.com
本研究旨在筛查鸭CD6 基因CDS 区的SNPs 位点及其与血清生化指标和肉质的关联性:
随机抽取同日出雏, 健康无病, 同等管理条件下饲喂10 周龄的100 只樱桃谷鸭, 133 …

A role of CD36 in the perception of an oxidised phospholipid species in mice

S Lee, A Eguchi, K Sakamoto, S Matsumura… - Biomedical …, 2015 - jstage.jst.go.jp
ABSTRACT CD36 is a broadly expressed transmembrane protein that engages multiple
ligands, including polar lipids. This protein is thought to even contribute to the …

[HTML][HTML] Thematic Review Series: Intestinal Lipid Metabolism: New Developments and Current Insights: Intestinal triacylglycerol synthesis in fat absorption and …

CLE Yen, DW Nelson, MI Yen - Journal of Lipid Research, 2015 - ncbi.nlm.nih.gov
The intestine plays a prominent role in the biosynthesis of triacylglycerol (triglyceride; TAG).
Digested dietary TAG is repackaged in the intestine to form the hydrophobic core of …