The concept that excess superoxide production from mitochondria is the driving, initial
cellular response underlying diabetes complications has been held for the past decade …

Diabetes is a complex disease with many serious potential sequelae, including large vessel
arterial disease and microvascular dysfunction. Peripheral arterial disease is a common …

The Diabetes Control and Complications Trial (DCCT) demonstrated that a mean of 6.5
years of intensive therapy aimed at near-normal glucose levels reduced the risk of …

Treatment-induced neuropathy in diabetes (also referred to as insulin neuritis) is considered
a rare iatrogenic small fibre neuropathy caused by an abrupt improvement in glycaemic …

Background & Aims After the Diabetes Control and Complications Trial (DCCT), the
Epidemiology of Diabetes Interventions and Complications (EDIC) study continued to show …

Six skin collagen advanced glycation end products (AGEs) originally measured near to the
time of the Diabetes Control and Complications Trial (DCCT) closeout in 1993 may …

Pharmacological Treatment Of Diabetic Peripheral Neuropathy - PMC Back to Top Skip to
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Neuropathic pain is defined as pain arising as a direct consequence of a lesion or a disease
affecting the somatosensory system and it affects around 1 in 4 diabetic patients in the UK …

Peripheral painful neuropathy is one of the most common complications in diabetes and
necessitates improved treatment. Fisetin, a naturally occurring flavonoid, has been reported …

ABSTRACT Type 1 diabetes (T1D) is an autoimmune disease characterized by progressive
pancreatic beta-cell loss resulting in insulin deficiency and hyperglycemia. Exogenous …