Introduction: Osteoarthritis (OA) is the most prevailing form of joint disease, with symptoms
affecting 10–12% of the adult population with a projection of a 50% increase in prevalence …

Osteoarthritis (OA) has long been a difficult to overcome joint disease for medical workers.
However, there is still a lack of effective treatments for OA. In the present study, we aimed to …

We have previously reported that intra-articular injection of xanthan gum (XG) could
significantly ameliorate the degree of joint cartilage degradation and pain in experimental …

Emergence of resistance to pentavalent antimonials has become a severe obstacle in the
treatment of visceral leishmaniasis (VL) in the Indian subcontinent. Mitogen-activated protein …

Osteoarthritis (OA) is the most common arthritis and also one of the major causes of joint
pain in elderly people. The aim of this study was to investigate the effects of pyrroloquinoline …

Salinomycin (SAL), a monocarboxylic polyether antibiotic isolated from Streptomyces albus,
modulates various cellular responses, including proliferation, apoptosis, and inflammation …

SIRT2 is a member of the mammalian sirtuin protein family, primarily found in the cytoplasm.
It regulates numerous cellular processes including aging, DNA repair, cell cycle, and …

The invention provides a method of effecting de-differentia tion of an at least partially
differentiated cellor of maintaining pluripotency and/or self-renewing characteristics of an …

Overexpression of Shc adaptor proteins is associated with mitogenesis, carcinogenesis and
metastasis. Multiple copies in T-cell malignancy 1 (MCT-1) oncoprotein promotes cell …

The burden of cancer is expanding at an alarming rate. As in 2012, approximately 14.1
million cancer cases and 8.8 million cancer deaths were reported worldwide. It is expected …