Abdominal aortic aneurysm: novel mechanisms and therapies

FM Davis, DL Rateri, A Daugherty - Current opinion in cardiology, 2015 - journals.lww.com
Abdominal aortic aneurysm: novel mechanisms and therapies : Current Opinion in
Cardiology Abdominal aortic aneurysm: novel mechanisms and therapies : Current Opinion …

Angiotensin II and abdominal aortic aneurysms: an update

J Liu, A Daugherty, H Lu - Current pharmaceutical design, 2015 - ingentaconnect.com
Abdominal aortic aneurysm (AAA) is a devastating disease associated with high prevalence
of death due to aortic rupture. Currently the therapy is restricted to surgical procedures to …

Thrombospondin-1 (TSP1) contributes to the development of vascular inflammation by regulating monocytic cell motility in mouse models of abdominal aortic …

Z Liu, S Morgan, J Ren, Q Wang, DS Annis… - Circulation …, 2015 - Am Heart Assoc
Rationale: Histological examination of abdominal aortic aneurysm (AAA) tissues
demonstrates extracellular matrix destruction and infiltration of inflammatory cells. Previous …

Subcutaneous angiotensin II infusion using osmotic pumps induces aortic aneurysms in mice

H Lu, DA Howatt, A Balakrishnan… - JoVE (Journal of …, 2015 - jove.com
Osmotic pumps continuously deliver compounds at a constant rate into small animals. This
article introduces a standard protocol used to induce aortic aneurysms via subcutaneous …

Thrombospondin-1: an extracellular message delivered by macrophages that promotes aortic aneurysms

EC Lessey-Morillon, DD Roberts - Circulation research, 2015 - Am Heart Assoc
114 Circulation Research July 3, 2015 cell autonomous. A deficit in macrophage recruitment
after thioglycollate injection into Thbs1−/− mice was reproduced when Thbs1 …

Extracellular matrix on the phenotypic switching of vascular smooth muscle cells

Z Chen, Y Fu, W Kong - Current Angiogenesis, 2015 - ingentaconnect.com
Background: Vascular smooth muscle cells (VSMCs) show eminently plasticity during
physiological and pathological processes. VSMCs undergo from contractile phenotype to …

The Role of ApoB-containing Lipoproteins in Abdominal Aortic Aneurysm

J Liu - 2015 - uknowledge.uky.edu
Abdominal aortic aneurysm (AAA) is a devastating disease that exhibits permanent lumen
expansion typically in the infrarenal aorta. AAA is prevalent among aged population …