Integrative utilization of microenvironments, biomaterials and computational techniques for advanced tissue engineering

A Shamloo, N Mohammadaliha, M Mohseni - Journal of biotechnology, 2015 - Elsevier
This review aims to propose the integrative implementation of microfluidic devices,
biomaterials, and computational methods that can lead to a significant progress in tissue …

Recording large extracellular spikes in microchannels along many axonal sites from individual neurons

MK Lewandowska, DJ Bakkum, SB Rompani… - PloS one, 2015 - journals.plos.org
The numerous connections between neuronal cell bodies, made by their dendrites and
axons, are vital for information processing in the brain. While dendrites and synapses have …

Control over neurite directionality and neurite elongation on anisotropic micropillar arrays.

M Park, E Oh, J Seo, MH Kim, H Cho… - Small (Weinheim an …, 2015 - europepmc.org
Control over Neurite Directionality and Neurite Elongation on Anisotropic Micropillar Arrays. -
Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC Menu About …

Rebuilding brain circuitry with living micro-tissue engineered neural networks

LA Struzyna, JA Wolf, CJ Mietus… - … Engineering Part A, 2015 - liebertpub.com
Prominent neuropathology following trauma, stroke, and various neurodegenerative
diseases includes neuronal degeneration as well as loss of long-distance axonal …

Effects of ECM protein micropatterns on the migration and differentiation of adult neural stem cells

S Joo, J Yeon Kim, E Lee, N Hong, W Sun, Y Nam - Scientific reports, 2015 - nature.com
The migration and differentiation of adult neural stem cells (aNSCs) are believed to be
strongly influenced by the spatial distribution of extracellular matrix (ECM) proteins in the …

Engineering cortical neuron polarity with nanomagnets on a chip

A Kunze, P Tseng, C Godzich, C Murray, A Caputo… - ACS …, 2015 - ACS Publications
Intra-and extracellular signaling play critical roles in cell polarity, ultimately leading to the
development of functional cell–cell connections, tissues, and organs. In the brain …

Polydimethylsiloxane SlipChip for mammalian cell culture applications

CW Chang, CC Peng, WH Liao, YC Tung - Analyst, 2015 - pubs.rsc.org
This paper reports a polydimethylsiloxane (PDMS) SlipChip for in vitro cell culture
applications, multiple-treatment assays, cell co-cultures, and cytokine detection assays. The …

In vitro neurite guidance effects induced by polylysine pinstripe micropatterns with polylysine background

S Joo, K Kang, Y Nam - … of biomedical materials research Part A, 2015 - Wiley Online Library
Engineered culture substrates with chemical neurite guidance cues have been used for
studying the mechanism of axon pathfinding at cellular level. In this study, we designed a …

A microfluidic device for generation of chemical gradients

Y Ge, Q An, Y Gao, Y Chen, D Li - Microsystem Technologies, 2015 - Springer
A microfluidic device was developed for generating chemical concentration gradients by
integrating PEG-diacrylate (PEGDA) hydrogel separators in a Polydimethylsiloxane (PDMS) …

Development of microfluidic devices for the manipulation of neuronal synapses

A Jain, MU Gillette - Microfluidic and Compartmentalized Platforms for …, 2015 - Springer
Key determinants in the development of complex morphology and function are the cues
present in a cell's environment and its response to them. Primary among these extracellular …