Classical and non-classical MHC I molecule manipulation by human cytomegalovirus: so many targets—but how many arrows in the quiver?

A Halenius, C Gerke, H Hengel - Cellular & molecular immunology, 2015 - nature.com
Major mechanisms for the recognition of pathogens by immune cells have evolved to
employ classical and non-classical major histocompatibility complex class I (MHC I) …

Functional and genetic diversity of leukocyte immunoglobulin-like receptor and implication for disease associations

K Hirayasu, H Arase - Journal of human genetics, 2015 - nature.com
Human leukocyte immunoglobulin-like receptors (LILR) are a family of 11 functional genes
encoding five activating (LILRA1, 2, 4–6), five inhibitory (LILRB1–5) and one soluble …

Overexpression of CD85j in TNBC patients inhibits Cetuximab‐mediated NK‐cell ADCC but can be restored with CD85j functional blockade

MP Roberti, EP Juliá, YS Rocca, M Amat… - European journal of …, 2015 - Wiley Online Library
Clinical studies suggest that triple negative breast cancer (TNBC) patients with epidermal
growth factor receptor (EGFR)‐expressing tumors could benefit from therapy with …

Clinical implication of human leukocyte antigen (HLA)‐F expression in breast cancer

A Harada, S Ishigami, Y Kijima, A Nakajo… - Pathology …, 2015 - Wiley Online Library
Human leukocyte antigen (HLA)‐F is one of the non‐classical HLA class I molecules that
protects the fetus in pregnancy. HLA‐F expression was immunohistochemically examined …

Lesion human leukocyte antigen‑F expression is associated with a poor prognosis in patients with hepatocellular carcinoma

Y Xu, H Han, F Zhang, S Lv, Z Li… - Oncology …, 2015 - spandidos-publications.com
Human leukocyte antigen (HLA)‑F, a non‑classical HLA‑class I molecule, has attracted
attention as an important immunosuppressive molecule in recent years, although the clinical …

[HTML][HTML] Co-expression of immunoglobulin-like transcript 4 and angiopoietin-like proteins in human non-small cell lung cancer

L Wang, T Geng, X Guo, J Liu… - Molecular …, 2015 - spandidos-publications.com
The development of strategies for the inhibition of non‑small cell lung cancer (NSCLC)
progression and metastasis have been mainly unsuccessful, in part due to insufficient …

[PDF][PDF] Immunobiology of HLA class-Ib molecules in transplantation

V Jucaud, MH Ravindranath, PI Terasaki - SOJ Immunol, 2015 - pdfs.semanticscholar.org
The objective of this review is to elucidate the role of HLA-Ib molecules in transplantation
after elucidating their immunobiological potential. Structurally, the non-classical HLA-Ib …

[PDF][PDF] Effects of cigarette smoke on killer cell activation in chronic obstructive pulmonary disease

J Wang - 2015 - core.ac.uk
FCS Foetal calf serum FEV1 forced expiratory volume in one second FGF fibroblast growth
factors FITC fluorescein isothiocyanate FMO fluorescence minus one FVC forced vital …

Specific removal of activated immune cells

DE Geraghty, N Lee - US Patent App. 14/678,564, 2015 - Google Patents
The present invention provides a method of detecting an immune response in a mammalian
subject by:(a) withdrawing blood or a blood fraction containing immune cells from the …

Ly49 RECEPTORS: REQUIREMENTS FOR LIGAND RECOGNITION AND STRUCTURAL ASSEMBLY

CM Craveiro Salvado - 2015 - era.library.ualberta.ca
Natural killer (NK) cells in the mouse and rat rely on homodimeric Ly49 receptors to detect
virally infected or transformed cells. The identification of altered cells requires the …