Significance: Microorganisms can exist both in the planktonic and biofilm state. Each
phenotypic state has a role to play in delaying healing and causing infections of both acute …

Significance: The presence of a “pathogenic” or “highly virulent” biofilm is a fundamental risk
factor that prevents a chronic wound from healing and increases the risk of the wound …

Significance: Biofilms have been implicated in a variety of wound complications. Recent
Advances: Research has confirmed that biofilms form in wounds of patients experiencing …

The presence of non-viable tissue in a chronic wound presents a barrier against effective
wound healing, hence removal facilitates healing and reduces areas where microorganisms …

Introduction: Chronic wounds represent a major health burden worldwide. It has been
hypothesized that the polymicrobial nature of wounds plays an important role in their healing …

Significance: Multispecies microbial biofilms may contribute to wound chronicity by derailing
the inherent reparative process of the host tissue. In the biofilm form, bacteria are encased …

Historically it has been accepted, and recent research has established, that silver (Ag) is an
efficacious antimicrobial agent. A dwindling pipeline of new antibiotics, combined with an …

Many diseases caused by Staphylococcus aureus are associated with biofilm formation.
However, the ability of S. aureus isolates from skin and soft tissue infections to form biofilms …

A biofilm can be described as a microbial colony encased in a polysaccharide matrix which
can become attached to a wound surface. This can affect the healing potential of chronic …

Objective: To assess the effectiveness of a new, next-generation antimicrobial dressing
(AQUACEL Ag+ dressing) in facilitating healing in a variety of hard-to-heal wounds that may …