PCSK9 inhibition with evolocumab (AMG 145) in heterozygous familial hypercholesterolaemia (RUTHERFORD-2): a randomised, double-blind, placebo-controlled …
Background Heterozygous familial hypercholesterolaemia is characterised by low cellular
uptake of LDL cholesterol, increased plasma LDL cholesterol concentrations, and premature …
uptake of LDL cholesterol, increased plasma LDL cholesterol concentrations, and premature …
Prevalence and management of familial hypercholesterolaemia in coronary patients: an analysis of EUROASPIRE IV, a study of the European Society of Cardiology
Background Familial hypercholesterolaemia (FH) is a hereditary disorder predisposing to
premature coronary heart disease (CHD) and is until now mainly diagnosed clinically on the …
premature coronary heart disease (CHD) and is until now mainly diagnosed clinically on the …
Familial hypercholesterolemia in Brazil: cascade screening program, clinical and genetic aspects
CE Jannes, RD Santos, PR de Souza Silva, L Turolla… - Atherosclerosis, 2015 - Elsevier
Background: There is little knowledge about familial hypercholesterolemia in Brazil. This
study presents the first results of genetic cascade screening performed in the city of Sao …
study presents the first results of genetic cascade screening performed in the city of Sao …
Antioxidant, hypolipidemic, and anti-angiotensin-1-converting enzyme properties of lemon (Citrus limon) and lime (Citrus aurantifolia) juices
Lemon (Citrus limon) and lime (Citrus aurantifolia) juices are used in folk medicine for the
management of hypertension and other cardiovascular diseases, but the mechanism of …
management of hypertension and other cardiovascular diseases, but the mechanism of …
[HTML][HTML] Statins: Cholesterol guidelines and Indian perspective
AS Menon, N Kotwal, Y Singh… - Indian Journal of …, 2015 - journals.lww.com
Statins have become an important drug in preventing the occurrence of atherosclerotic
cardiovascular disease (ASCVD). The effectiveness of statins in reducing ASCVD has been …
cardiovascular disease (ASCVD). The effectiveness of statins in reducing ASCVD has been …
[HTML][HTML] Заключение совета экспертов Национального общества по изучению атеросклероза (НОА). Семейная гиперхолестеринемия в Российской …
ЮА Карпов, ВВ Кухарчук, СА Бойцов - Атеросклероз и …, 2015 - cyberleninka.ru
Нарушения липидного обмена вносят существенный вклад в развитие осложнений
атеросклероза. Семейная гиперхолестеринемия (СГХС) является наиболее частой …
атеросклероза. Семейная гиперхолестеринемия (СГХС) является наиболее частой …
Challenges in the care of familial hypercholesterolemia: a community care perspective
T Brett, GF Watts, DE Arnold-Reed, DA Bell… - Expert Review of …, 2015 - Taylor & Francis
Familial hyperchoelsterolaemia (FH) remains under-diagnosed and under-treated in the
community setting. Earlier evidence suggested a prevalence of 1: 500 worldwide but newer …
community setting. Earlier evidence suggested a prevalence of 1: 500 worldwide but newer …
LDL-R promoting activity of peptides derived from human PCSK9 catalytic domain (153–421): design, synthesis and biochemical evaluation
RH Alghamdi, P O'Reilly, C Lu, J Gomes… - European journal of …, 2015 - Elsevier
Abstract Background High level of Low Density Lipoprotein-Cholesterol (LDL-C) in
circulation in the blood is associated with an elevated risk of cardiovascular disease (CVD) …
circulation in the blood is associated with an elevated risk of cardiovascular disease (CVD) …
Cost-effectiveness analysis of alternative screening and treatment strategies for heterozygous familial hypercholesterolemia in the United States
CX Chen, JW Hay - International journal of cardiology, 2015 - Elsevier
Background/objectives Familial hypercholesterolemia (FH) is a genetic disorder that leads to
premature heart disease or stroke if untreated. Statins are effective for individuals with FH …
premature heart disease or stroke if untreated. Statins are effective for individuals with FH …
Cascade screening of familial hypercholesterolemia must go on
JMH Galema-Boers, J Versmissen, HWOR van Lennep… - Atherosclerosis, 2015 - Elsevier
Purpose This study assesses the success of the recently terminated Dutch nationwide
cascade screening by examining whether children with familial hypercholesterolemia (FH) …
cascade screening by examining whether children with familial hypercholesterolemia (FH) …