Background The genesis of severe fatigue and disability in people following acute pathogen
invasion involves the activation of Toll-like receptors followed by the upregulation of …

Traditionally, multiple sclerosis (MS) is considered to be a disease primarily affecting the
white matter (WM). However, the development of some clinical symptoms such as cognitive …

Objective: Increasing evidence indicates that the thalamus may be a location of early
neurodegeneration in multiple sclerosis (MS). Our objective was to identify the presence of …

In this multicenter study, we performed a tractography‐based parcellation of the thalamus
and its white matter connections to investigate the relationship between thalamic …

Introduction Gray matter (GM) atrophy is common in multiple sclerosis (MS), but the
relationship with white matter (WM) pathology is largely unknown. Some studies found a co …

In multiple sclerosis (MS), cerebellar signs and symptoms as well as cognitive dysfunction
are frequent and contribute to clinical disability with only poor response to symptomatic …

Putamen atrophy and its long-term progress during disease course were recently shown in
patients with multiple sclerosis (MS). Here we investigated retrospectively the time point of …

Our ability to control and inhibit behaviours that are inappropriate, unsafe, or no longer
required is crucial for functioning successfully in complex environments. Here, we …

Regional gray matter (GM) atrophy in multiple sclerosis (MS) at disease onset and its
temporal variation can provide objective information regarding disease evolution. An …

Brain atrophy has been identified as an important contributing factor to the development of
disability in multiple sclerosis (MS). In this respect, more and more interest is focussing on …