The study of the dynamics and functions of microglia in the healthy and diseased brain is a
matter of intense scientific activity. The application of new techniques and new experimental …

Neurodegeneration is a chronic progressive loss of neuronal cells leading to deterioration of
central nervous system (CNS) functionality. It has been shown that neuroinflammation …

The cannabinoid CB 2 receptor has recently emerged as a potential anti-inflammatory target
to break the self-sustaining cycle of neuroinflammation and neurodegeneration that is …

Inflammation is a predominant aspect of neurodegenerative diseases, manifested by glia
activation and expression of pro-inflammatory mediators. Studies on animal models of …

Atrazine (2-chloro-4-ethytlamino-6-isopropylamine-1, 3, 5-triazine; ATR) is a broad-spectrum
herbicide with a wide range of applications worldwide. However, ATR is neurotoxic; it …

Available evidence increasingly suggests that the degeneration of dopamine neurons in
Parkinson's disease starts in the striatal axons and synaptic terminals. A selective procedure …

Our recent study has indicated that a moderate lesion of the mesostriatal and mesolimbic
pathways in rats, modelling preclinical stages of Parkinson's disease, induces a depressive …

Macrophages are a well recognized player of both innate and adaptive immunity and have
emerged as a key regulator of systemicmetabolism, hematopoiesis, vasculogenesis …

It is well established that neuroinflammation is associated with the progression of many
neurodegenerative diseases, including Parkinson's disease (PD). Activated microglia and …

Parkinson's disease (PD) is characterised by the progressive neurodegeneration of the
nigrostriatal dopaminergic neurons that results in motor deficits including bradykinesia …