Rabbit models for the study of human atherosclerosis: from pathophysiological mechanisms to translational medicine
Laboratory animal models play an important role in the study of human diseases. Using
appropriate animals is critical not only for basic research but also for the development of …
appropriate animals is critical not only for basic research but also for the development of …
Characterization of anti-CD20 monoclonal antibody produced by transgenic silkworms (Bombyx mori)
M Tada, KI Tatematsu, A Ishii-Watabe, A Harazono… - MAbs, 2015 - Taylor & Francis
In response to the successful use of monoclonal antibodies (mAbs) in the treatment of
various diseases, systems for expressing recombinant mAbs using transgenic animals or …
various diseases, systems for expressing recombinant mAbs using transgenic animals or …
Generation of induced pluripotent stem cells from domestic goats
SES Sandmaier, A Nandal, A Powell… - Molecular …, 2015 - Wiley Online Library
The creation of genetically modified goats provides a powerful approach for improving
animal health, enhancing production traits, animal pharming, and for ensuring food safety all …
animal health, enhancing production traits, animal pharming, and for ensuring food safety all …
[图书][B] Molecular structures and structural dynamics of prion proteins and prions
J Zhang - 2015 - Springer
Studies conducted over the past few decades have demonstrated that rabbits are immune to
prion diseases (also known as transmissible spongiform encephalopathies (TSEs)). Unlike …
prion diseases (also known as transmissible spongiform encephalopathies (TSEs)). Unlike …
Post-translational modification of a chimeric EPO-Fc hormone is more important than its molecular size in defining its in vivo hematopoietic activity
ER Salgado, R Montesino, SP Jiménez… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Background Recombinant erythropoietin (EPO) has been marketed as biopharmaceutical
for anemia and chronic renal failure. Long-acting EPO variants that aimed at achieving less …
for anemia and chronic renal failure. Long-acting EPO variants that aimed at achieving less …
Adeno-associated-virus-mediated transduction of the mammary gland enables sustained production of recombinant proteins in milk
S Wagner, R Thresher, R Bland, G Laible - Scientific Reports, 2015 - nature.com
Biopharming for the production of recombinant pharmaceutical proteins in the mammary
gland of transgenic animals is an attractive but laborious alternative compared to …
gland of transgenic animals is an attractive but laborious alternative compared to …
Transgenic farm animals: Status of the current researches and the future
NA Zinovieva, NA Volkova, VA Bagirov… - Ecological …, 2015 - journals.eco-vector.com
The production of transgenic farm animals is of great interest of modern basic and applied
researches. This article reviews methods for production of transgenic farm animals including …
researches. This article reviews methods for production of transgenic farm animals including …
转基因动物乳腺生物反应器相关技术及研究进展
梁振鑫， 尹富强， 刘庆友， 李力 - 中国生物工程杂志, 2015 - manu60.magtech.com.cn
转基因动物乳腺生产人类重组蛋白人血清白蛋白(hSA), 人纤维蛋白原(hFIB), 人蛋白C (hPC),
人凝血因子(hF-Ⅷ) 和(hF-Ⅸ) 等具有较高市场潜力, 使其在医学领域获得广泛应用 …
人凝血因子(hF-Ⅷ) 和(hF-Ⅸ) 等具有较高市场潜力, 使其在医学领域获得广泛应用 …
重组人凝血因子Ⅶ 的研究进展
朱琳， 楼觉人 - 国际生物制品学杂志, 2015 - ijbiol.com
人凝血因子Ⅶ (human coagulation factor Ⅶ, hFⅦ) 是参与血液凝血级联反应的蛋白之一,
在凝血过程中发挥极其重要的作用. hFⅦ 主要用于治疗和预防先天性或获得性血友病患者的 …
在凝血过程中发挥极其重要的作用. hFⅦ 主要用于治疗和预防先天性或获得性血友病患者的 …
Establishment and exogenous genes expression analysis of cell strains secreted human interferon alpha 2b.
LUO Chan, QU Chun-feng, LI Hui… - Journal of Southern …, 2015 - search.ebscohost.com
Abstract [Objective] The present study was conducted to investigate application of uffalo
mammary gland bioreactor in production of human interferon alpha 2b (IFNα-2b) and the …
mammary gland bioreactor in production of human interferon alpha 2b (IFNα-2b) and the …