Circular RNA: a new star of noncoding RNAs

S Qu, X Yang, X Li, J Wang, Y Gao, R Shang, W Sun… - Cancer letters, 2015 - Elsevier
Circular RNAs (circRNAs) are a novel type of RNA that, unlike linear RNAs, form a
covalently closed continuous loop and are highly represented in the eukaryotic …

LncRNA HOTAIR: A master regulator of chromatin dynamics and cancer

A Bhan, SS Mandal - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2015 - Elsevier
Non-coding RNAs (ncRNAs) are emerging classes of regulatory RNA that play key roles in
various cellular and physiological processes such as in gene regulation, chromatin …

Long noncoding RNA MALAT1 promotes aggressive renal cell carcinoma through Ezh2 and interacts with miR-205

H Hirata, Y Hinoda, V Shahryari, G Deng, K Nakajima… - Cancer research, 2015 - AACR
Recently, long noncoding RNAs (lncRNA) have emerged as new gene regulators and
prognostic markers in several cancers, including renal cell carcinoma (RCC). In this study …

Long non-coding RNA CCAT1 promotes gallbladder cancer development via negative modulation of miRNA-218-5p

MZ Ma, BF Chu, Y Zhang, MZ Weng, YY Qin… - Cell death & …, 2015 - nature.com
Protein-coding genes account for only~ 2% of the human genome, whereas the vast majority
of transcripts are non-coding RNAs (ncRNAs) including long ncRNAs (lncRNAs). A growing …

Emerging role of long noncoding RNAs in autoimmune diseases

GC Wu, HF Pan, RX Leng, DG Wang, XP Li, XM Li… - Autoimmunity …, 2015 - Elsevier
Long noncoding RNA (lncRNA), with size larger than 200 nucleotides, is a new class of
noncoding RNA. Emerging evidence has revealed that lncRNAs play a key role in the …

Constructing lncRNA functional similarity network based on lncRNA-disease associations and disease semantic similarity

X Chen, C Clarence Yan, C Luo, W Ji, Y Zhang… - Scientific reports, 2015 - nature.com
Increasing evidence has indicated that plenty of lncRNAs play important roles in many
critical biological processes. Developing powerful computational models to construct …

[HTML][HTML] The interaction between MiR-141 and lncRNA-H19 in regulating cell proliferation and migration in gastric cancer

X Zhou, F Ye, C Yin, Y Zhuang, G Yue… - Cellular Physiology and …, 2015 - karger.com
Background/Aims: Non-coding RNAs including miRNA and lncRNA had been reported to
regulate gene expression and were both related to cancer progression. MicroRNA-141 (miR …

The fusion of two worlds: Non-coding RNAs and extracellular vesicles-diagnostic and therapeutic implications

Y Sato-Kuwabara, SA Melo… - … journal of oncology, 2015 - spandidos-publications.com
The role of the extracellular non-coding RNAs, particularly microRNAs present in tumor-
derived extravesicles, has been intensively exploited in human cancer as a promising tool …

Up-regulation of long noncoding RNA MALAT1 contributes to proliferation and metastasis in esophageal squamous cell carcinoma

L Hu, Y Wu, D Tan, H Meng, K Wang, Y Bai… - Journal of experimental & …, 2015 - Springer
Abstract Background Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1)
has been demonstrated to be an important player in various human malignancies; it is …

Progress and prospects of long noncoding RNAs (lncRNAs) in hepatocellular carcinoma

C Li, J Chen, K Zhang, B Feng, R Wang… - Cellular Physiology and …, 2015 - karger.com
Hepatocellular carcinoma (HCC) is one of the most frequently occurring cancers with poor
prognosis, and novel diagnostic or prognostic biomarkers and therapeutic targets for HCC …