Complicating autoimmune diseases in myasthenia gravis: a review

A Nacu, JB Andersen, V Lisnic, JF Owe, NE Gilhus - Autoimmunity, 2015 - Taylor & Francis
Myasthenia gravis (MG) is a rare autoimmune disease of skeletal muscle endplates. MG
subgroup is relevant for comorbidity, but usually not accounted for. MG patients have an …

Thymoma related myasthenia gravis in humans and potential animal models

A Marx, S Porubsky, D Belharazem… - Experimental …, 2015 - Elsevier
Thymoma-associated Myasthenia gravis (TAMG) is one of the anti-acetylcholine receptor
MG (AChR-MG) subtypes. The clinico-pathological features of TAMG and its pathogenesis …

Clinical features and diagnostic usefulness of antibodies to clustered acetylcholine receptors in the diagnosis of seronegative myasthenia gravis

PMR Cruz, M Al-Hajjar, S Huda, L Jacobson… - JAMA …, 2015 - jamanetwork.com
Importance Cell-based assays (CBAs) were shown to improve detection of acetylcholine
receptor (AChR) antibodies in patients with myasthenia gravis (MG). Herein, we asked …

MuSK autoantibodies in myasthenia gravis detected by cell based assay—a multinational study

AI Tsonis, P Zisimopoulou, K Lazaridis, J Tzartos… - Journal of …, 2015 - Elsevier
Seronegative myasthenia gravis (MG) presents a serious gap in MG diagnosis and
understanding. We applied a cell based assay (CBA) for the detection of muscle specific …

[HTML][HTML] Differential cytokine changes in patients with myasthenia gravis with antibodies against AChR and MuSK

V Yilmaz, P Oflazer, F Aysal, H Durmus, K Poulas… - PloS one, 2015 - journals.plos.org
Neuromuscular transmission failure in myasthenia gravis (MG) is most commonly elicited by
autoantibodies (ab) to the acetylcholine receptor or the muscle-specific kinase, constituting …

[HTML][HTML] Flow cytofluorimetric analysis of anti-LRP4 (LDL receptor-related protein 4) autoantibodies in Italian patients with myasthenia gravis

M Marino, F Scuderi, D Samengo, G Saltelli, MT Maiuri… - PloS one, 2015 - journals.plos.org
Background Myasthenia gravis (MG) is an autoimmune disease in which 90% of patients
have autoantibodies against the muscle nicotinic acetylcholine receptor (AChR), while …

重症肌无力免疫学机制研究进展

李媛, 楚兰, 张艺凡 - 中国神经免疫学和神经病学杂志, 2015 - cqvip.com
重症肌无力(MG) 是一种神经肌肉接头(NMJ) 传递障碍的获得性自身免疫性疾病,
发病机制主要以体液免疫为主, 细胞免疫依赖及补体参与. 研究表明, MG 的发病与多种淋巴细胞 …

Forced expression of muscle specific kinase slows postsynaptic acetylcholine receptor loss in a mouse model of Mu SK myasthenia gravis

N Ghazanfari, ELTB Linsao, S Trajanovska… - Physiological …, 2015 - Wiley Online Library
We investigated the influence of postsynaptic tyrosine kinase signaling in a mouse model of
muscle‐specific kinase (Mu SK) myasthenia gravis (MG). Mice administered repeated daily …

Characteristics of myasthenia gravis with antibodies to muscle‐specific kinase and low‐density lipoprotein‐related receptor protein 4

A Evoli, R Iorio - Clinical and Experimental Neuroimmunology, 2015 - Wiley Online Library
Myasthenia gravis (MG) is characterized by fatigable weakness of voluntary muscles caused
by immunoglobulin G autoantibodies binding to post‐synaptic proteins at the neuromuscular …

重症肌无力诊断与治疗最新进展

刘书平, 李承晏 - 卒中与神经疾病, 2015 - cqvip.com
重症肌无力(myasthenia gravis, MG) 是一种神经肌肉接头传递障碍疾病, 以骨骼肌无力,
晨轻暮重, 症状有波动为主要临床特点. 近年来老年MG 的发病率逐年增加 …