Acute lymphoblastic leukemia in children
SP Hunger, CG Mullighan - New England Journal of Medicine, 2015 - Mass Medical Soc
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Childhood acute lymphoblastic leukemia: progress through collaboration
CH Pui, JJ Yang, SP Hunger, R Pieters… - Journal of Clinical …, 2015 - ascopubs.org
Purpose To review the impact of collaborative studies on advances in the biology and
treatment of acute lymphoblastic leukemia (ALL) in children and adolescents. Methods A …
treatment of acute lymphoblastic leukemia (ALL) in children and adolescents. Methods A …
Redefining ALL classification: toward detecting high-risk ALL and implementing precision medicine
SP Hunger, CG Mullighan - Blood, The Journal of the American …, 2015 - ashpublications.org
Acute lymphoblastic leukemia (ALL) is the commonest childhood tumor and remains a
leading cause of cancer death in the young. In the last decade, microarray and sequencing …
leading cause of cancer death in the young. In the last decade, microarray and sequencing …
Biology of childhood acute lymphoblastic leukemia
D Bhojwani, JJ Yang, CH Pui - Pediatric Clinics, 2015 - pediatric.theclinics.com
Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy, accounting
for 25% of all childhood cancers. In the United States, approximately 3000 children aged 1 …
for 25% of all childhood cancers. In the United States, approximately 3000 children aged 1 …
Genomics in acute lymphoblastic leukaemia: insights and treatment implications
KG Roberts, CG Mullighan - Nature reviews Clinical oncology, 2015 - nature.com
Acute lymphoblastic leukaemia (ALL) is the commonest childhood cancer and an important
cause of morbidity from haematological malignancies in adults. In the past several years, we …
cause of morbidity from haematological malignancies in adults. In the past several years, we …
How I treat acute lymphoblastic leukemia in older adolescents and young adults
E Curran, W Stock - Blood, The Journal of the American Society …, 2015 - ashpublications.org
At the intersection between children and older adults, the care of adolescent and young
adult (AYA) patients with acute lymphoblastic leukemia (ALL) poses unique challenges and …
adult (AYA) patients with acute lymphoblastic leukemia (ALL) poses unique challenges and …
Childhood acute lymphoblastic leukemia: Integrating genomics into therapy
Acute lymphoblastic leukemia (ALL), the most common malignancy of childhood, is a
genetically complex entity that remains a major cause of childhood cancer‐related mortality …
genetically complex entity that remains a major cause of childhood cancer‐related mortality …
Outcome of children with hypodiploid ALL treated with risk-directed therapy based on MRD levels
CG Mullighan, S Jeha, D Pei… - Blood, The Journal …, 2015 - ashpublications.org
Hypodiploid acute lymphoblastic leukemia (ALL) with, 45 chromosomes has been
associated with a dismal prognosis. 1-4 Near-haploid (24-31 chromosomes) and low …
associated with a dismal prognosis. 1-4 Near-haploid (24-31 chromosomes) and low …
Acute lymphoblastic leukemia
CJ Harrison, B Johansson - … Cytogenetics: Chromosomal and …, 2015 - Wiley Online Library
Acute lymphoblastic leukemia (ALL) is classified as B‐lineage ALL (B‐ALL) and T‐lineage
ALL (T‐ALL). The incidence of ALL is almost three times higher in white than black children …
ALL (T‐ALL). The incidence of ALL is almost three times higher in white than black children …
Ikaros and leukaemia
L Olsson, B Johansson - British journal of haematology, 2015 - Wiley Online Library
The IKZF 1 gene at 7p12. 2 codes for IKAROS (also termed IKZF 1), an essential
transcription factor in haematopoiesis involved primarily in lymphoid differentiation. Its …
transcription factor in haematopoiesis involved primarily in lymphoid differentiation. Its …