Regulation and Evolution of the RAG Recombinase
G Teng, DG Schatz - Advances in immunology, 2015 - Elsevier
The modular, noncontiguous architecture of the antigen receptor genes necessitates their
assembly through V (D) J recombination. This program of DNA breakage and rejoining …
assembly through V (D) J recombination. This program of DNA breakage and rejoining …
[PDF][PDF] Arabidopsis AT-hook protein TEK positively regulates the expression of arabinogalactan proteins for nexine formation
QS Jia, J Zhu, XF Xu, Y Lou, ZL Zhang, ZP Zhang… - Molecular plant, 2015 - cell.com
Nexine is a conserved layer of the pollen wall. We previously reported that the nexine layer
is absent in the knockout mutant of Arabidopsis TRANSPOSABLE ELEMENT SILENCING …
is absent in the knockout mutant of Arabidopsis TRANSPOSABLE ELEMENT SILENCING …
The extended AT-hook is a novel RNA binding motif
M Filarsky, K Zillner, I Araya, A Villar-Garea, R Merkl… - RNA biology, 2015 - Taylor & Francis
The AT-hook has been defined as a DNA binding peptide motif that contains a glycine-
arginine-proline (GRP) tripeptide core flanked by basic amino acids. Recent reports …
arginine-proline (GRP) tripeptide core flanked by basic amino acids. Recent reports …
[HTML][HTML] The AT-Hook motif as a versatile minor groove anchor for promoting DNA binding of transcription factor fragments
J Rodríguez, J Mosquera, JR Couceiro… - Chemical …, 2015 - pubs.rsc.org
We report the development of chimeric DNA binding peptides comprising a DNA binding
fragment of natural transcription factors (the basic region of a bZIP protein or a monomeric …
fragment of natural transcription factors (the basic region of a bZIP protein or a monomeric …
De novo truncating variants in the AHDC1 gene encoding the AT-hook DNA-binding motif-containing protein 1 are associated with intellectual disability and …
H Yang, G Douglas… - Molecular …, 2015 - molecularcasestudies.cshlp.org
Whole-exome sequencing (WES) represents a significant breakthrough in clinical genetics,
and identifies a genetic etiology in up to 30% of cases of intellectual disability (ID). Using …
and identifies a genetic etiology in up to 30% of cases of intellectual disability (ID). Using …
Distinct self-interaction domains promote Multi Sex Combs accumulation in and formation of the Drosophila histone locus body
EA Terzo, SM Lyons, JS Poulton… - Molecular Biology of …, 2015 - Am Soc Cell Biol
Nuclear bodies (NBs) are structures that concentrate proteins, RNAs, and
ribonucleoproteins that perform functions essential to gene expression. How NBs assemble …
ribonucleoproteins that perform functions essential to gene expression. How NBs assemble …
[HTML][HTML] Molecular mechanism of Spinocerebellar Ataxia type 6: glutamine repeat disorder, channelopathy and transcriptional dysregulation. The multifaceted aspects …
P Giunti, E Mantuano, M Frontali… - Frontiers in cellular …, 2015 - frontiersin.org
Spinocerebellar Ataxia type 6 (SCA6) is an autosomal dominant neurodegenerative disease
characterized by late onset, slowly progressive, mostly pure cerebellar ataxia. It is one of …
characterized by late onset, slowly progressive, mostly pure cerebellar ataxia. It is one of …
A de novo t(10;19)(q22.3;q13.33) leads to ZMIZ1/PRR12 reciprocal fusion transcripts in a girl with intellectual disability and neuropsychiatric alterations
C Córdova-Fletes, MG Domínguez, I Delint-Ramirez… - Neurogenetics, 2015 - Springer
We report a girl with intellectual disability (ID), neuropsychiatric alterations, and a de novo
balanced t (10; 19)(q22. 3; q13. 33) translocation. After chromosome sorting, fine mapping of …
balanced t (10; 19)(q22. 3; q13. 33) translocation. After chromosome sorting, fine mapping of …
A novel RNA binding surface of the TAM domain of TIP5/BAZ2A mediates epigenetic regulation of rRNA genes
I Anosova, S Melnik, K Tripsianes, F Kateb… - Nucleic acids …, 2015 - academic.oup.com
The chromatin remodeling complex NoRC, comprising the subunits SNF2h and
TIP5/BAZ2A, mediates heterochromatin formation at major clusters of repetitive elements …
TIP5/BAZ2A, mediates heterochromatin formation at major clusters of repetitive elements …
NUCKS: a potential biomarker in cancer and metabolic disease
B Qiu, W Han, V Tergaonkar - Clinical Science, 2015 - portlandpress.com
Nuclear, casein kinase and cyclin-dependent kinase substrate (NUCKS), a protein similar to
the HMG (high-mobility group) protein family, is one of the most modified proteins in the …
the HMG (high-mobility group) protein family, is one of the most modified proteins in the …