MSCs are an extensively used cell type in clinical trials today. The initial rationale for their
clinical testing was based on their differentiation potential. However, the lack of correlation …

Cardiac tissue damage due to myocardial infarction (MI) is one of the leading causes of
mortality worldwide. The available treatments of MI include pharmaceutical therapy, medical …

This study is aimed at investigating whether human umbilical cord mesenchymal stem cell‐
(hucMSC‐) derived exosomes (hucMSC‐exosomes) have a protective effect on acute …

Rationale: Tissue engineering approaches may improve survival and functional benefits
from human embryonic stem cell–derived cardiomyocyte transplantation, thereby potentially …

Tendon injuries represent a significant clinical burden on healthcare systems worldwide. As
the human population ages and the life expectancy increases, tendon injuries will become …

Regenerative medicine relying on cell and gene therapies is one of the most promising
approaches to repair tissues. Multipotent mesenchymal stem/stromal cells (MSC), a …

Periodontitis is a inflammation induced by a bacterial infection that causes the destruction of
the attachment apparatus of dental roots. Several materials, such as bone graft materials …

Mesenchymal stem cells (MSCs) have rapidly been applied in a broad field of immune-
mediated disorders since the first successful clinical use of MSCs for treatment of graft …

Adipose-derived stem cells (ASCs) are prevalent surrounding the blood vessels and within
the connective tissue of human adipose tissue. These non–lipid-laden stromal cells can be …

The overall clinical cardiac regeneration experience suggests that stem cell therapy can be
safely performed, but it also underlines the need for reproducible results for their effective …