Computational prediction of RNA-binding proteins and binding sites

J Si, J Cui, J Cheng, R Wu - International journal of molecular sciences, 2015 - mdpi.com
Proteins and RNA interaction have vital roles in many cellular processes such as protein
synthesis, sequence encoding, RNA transfer, and gene regulation at the transcriptional and …

Structural modeling from electron microscopy data

JR López‐Blanco, P Chacón - Wiley Interdisciplinary Reviews …, 2015 - Wiley Online Library
Cryo‐electron microscopy is a powerful technique for the determination of three‐
dimensional (3D) structures of macromolecular machines, as it provides functional …

Modeling of ribonucleic acid–ligand interactions

F Stefaniak, EI Chudyk, M Bodkin… - Wiley …, 2015 - Wiley Online Library
Computational methods play a pivotal role in the early stages of small molecule drug
discovery and are widely applied in virtual screening, structure optimization, and compound …

Evolution of macromolecular docking techniques: the case study of nickel and iron metabolism in pathogenic bacteria

F Musiani, S Ciurli - Molecules, 2015 - mdpi.com
The interaction between macromolecules is a fundamental aspect of most biological
processes. The computational techniques used to study protein-protein and protein-nucleic …