HDL particle size is a critical determinant of ABCA1-mediated macrophage cellular cholesterol export
XM Du, MJ Kim, L Hou, W Le Goff… - Circulation …, 2015 - Am Heart Assoc
Rationale: High-density lipoprotein (HDL) is a heterogeneous population of particles.
Differences in the capacities of HDL subfractions to remove cellular cholesterol may explain …
Differences in the capacities of HDL subfractions to remove cellular cholesterol may explain …
[HTML][HTML] Human genetics of HDL: insight into particle metabolism and function
LR Brunham, MR Hayden - Progress in lipid research, 2015 - Elsevier
Levels of high-density lipoprotein cholesterol (HDL-C) are inversely related to
cardiovascular disease risk and HDL particles possess a variety of anti-atherosclerotic …
cardiovascular disease risk and HDL particles possess a variety of anti-atherosclerotic …
Innovative pharmaceutical interventions in cardiovascular disease: Focusing on the contribution of non-HDL-C/LDL-C-lowering versus HDL-C-raisingA systematic …
S Kühnast, M Fiocco, JWA van der Hoorn… - European journal of …, 2015 - Elsevier
Non-HDL-cholesterol is well recognised as a primary causal risk factor in cardiovascular
disease. However, despite consistent epidemiological evidence for an inverse association …
disease. However, despite consistent epidemiological evidence for an inverse association …
[PDF][PDF] ApoA-I mimetics
RM Stoekenbroek, ES Stroes… - … Understanding to Clinical …, 2015 - library.oapen.org
A wealth of evidence indicates that plasma levels of high-density lipoprotein cholesterol
(HDL-C) are inversely related to the risk of cardiovascular disease (CVD). Consequently …
(HDL-C) are inversely related to the risk of cardiovascular disease (CVD). Consequently …
[HTML][HTML] High-density lipoprotein-targeted therapy and apolipoprotein AI mimetic peptides
Y Uehara, G Chiesa, K Saku - Circulation Journal, 2015 - jstage.jst.go.jp
Numerous randomized clinical trials have established statins as the major standard therapy
for atherosclerotic diseases because these molecules decrease the plasma level of low …
for atherosclerotic diseases because these molecules decrease the plasma level of low …
ApoA-I-directed therapies for the management of atherosclerosis
JS Millar, M Cuchel - Current atherosclerosis reports, 2015 - Springer
Several recent reports have raised doubts about the atheroprotective role of high-density
lipoprotein cholesterol (HDL-C). Nevertheless, a substantial body of work supports the …
lipoprotein cholesterol (HDL-C). Nevertheless, a substantial body of work supports the …
Therapeutic ultrasound: increased HDL-cholesterol following infusions of acoustic microspheres and apolipoprotein AI plasmids
JW Castle, KP Kent, Y Fan, KD Wallace, CEL Davis… - Atherosclerosis, 2015 - Elsevier
Background Low levels of HDL-C are an independent cardiovascular risk factor associated
with increased premature cardiovascular death. However, HDL-C therapies historically have …
with increased premature cardiovascular death. However, HDL-C therapies historically have …
Acute high-density lipoprotein therapies
MN Duong, BA Di Bartolo… - Current Opinion in …, 2015 - journals.lww.com
Acute high-density lipoprotein therapies : Current Opinion in Lipidology Acute high-density
lipoprotein therapies : Current Opinion in Lipidology Log in or Register Subscribe to journalSubscribe …
lipoprotein therapies : Current Opinion in Lipidology Log in or Register Subscribe to journalSubscribe …
High‐Density Lipoprotein Therapies—Then and Now
HJ Pownall, C Rosales, BK Gillard… - Atherosclerosis: Risks …, 2015 - Wiley Online Library
High‐density lipoproteins (HDLs) are antiatherogenic through their role in reverse
cholesterol transport (RCT), that is, the transfer of cholesterol from macrophages in the …
cholesterol transport (RCT), that is, the transfer of cholesterol from macrophages in the …
[PDF][PDF] Twenty-five years of statins: where do we go from here
AM Gotto Jr, JE Moon - Clin Lipidol, 2015 - pharmaconconsulting.com
More than 25 years of clinical trial data have established statins as first-line therapy for the
prevention and treatment of atherosclerotic cardiovascular disease. With regard to low …
prevention and treatment of atherosclerotic cardiovascular disease. With regard to low …