Advances in 3D cell culture technologies enabling tissue‐like structures to be created in vitro

E Knight, S Przyborski - Journal of anatomy, 2015 - Wiley Online Library
Research in mammalian cell biology often relies on developing in vitro models to enable the
growth of cells in the laboratory to investigate a specific biological mechanism or process …

An overview of injectable polymeric hydrogels for tissue engineering

A Sivashanmugam, RA Kumar, MV Priya… - European Polymer …, 2015 - Elsevier
The desire and need to minimize traditional open surgeries is gearing up as it could reduce
the healthcare expenses and improve the recovery time for the patients. Minimal invasive …

Tissue adhesive catechol‐modified hyaluronic acid hydrogel for effective, minimally invasive cell therapy

J Shin, JS Lee, C Lee, HJ Park, K Yang… - Advanced Functional …, 2015 - Wiley Online Library
Current hyaluronic acid (HA) hydrogel systems often cause cytotoxicity to encapsulated cells
and lack the adhesive property required for effective localization of transplanted cells in vivo …

Fabrication of polymeric biomaterials: a strategy for tissue engineering and medical devices

F Khan, M Tanaka, SR Ahmad - Journal of Materials Chemistry B, 2015 - pubs.rsc.org
Polymeric biomaterials have a significant impact in today's health care technology. Polymer
hydrogels were the first experimentally designed biomaterials for human use. In this article …

Peptide bioink: self-assembling nanofibrous scaffolds for three-dimensional organotypic cultures

Y Loo, A Lakshmanan, M Ni, LL Toh, S Wang… - Nano …, 2015 - ACS Publications
Printable scaffolds with adequate mechanical strength and stiffness are sought after to
ensure viability of printed cells and tissues. We report the first peptide bioinks–lysine …

Three-dimensional bioprinting of embryonic stem cells directs highly uniform embryoid body formation

L Ouyang, R Yao, S Mao, X Chen, J Na, W Sun - Biofabrication, 2015 - iopscience.iop.org
With the ability to manipulate cells temporarily and spatially into three-dimensional (3D)
tissue-like construct, 3D bioprinting technology was used in many studies to facilitate the …

Liver-Tumor Hybrid Organoids for Modeling Tumor Growth and Drug Response In Vitro

A Skardal, M Devarasetty, C Rodman, A Atala… - Annals of biomedical …, 2015 - Springer
Current in vitro models for tumor growth and metastasis are poor facsimiles of in vivo cancer
physiology and thus, are not optimal for anti-cancer drug development. Three dimensional …

Human embryonic stem cell cultivation: historical perspective and evolution of xeno-free culture systems

N Desai, P Rambhia, A Gishto - Reproductive Biology and Endocrinology, 2015 - Springer
Human embryonic stem cells (hESC) have emerged as attractive candidates for cell-based
therapies that are capable of restoring lost cell and tissue function. These unique cells are …

On human pluripotent stem cell control: The rise of 3D bioengineering and mechanobiology

Y Shao, J Sang, J Fu - Biomaterials, 2015 - Elsevier
Human pluripotent stem cells (hPSCs) provide promising resources for regenerating tissues
and organs and modeling development and diseases in vitro. To fulfill their promise, the fate …

Extrusion bioprinting

F Pati, J Jang, JW Lee, DW Cho - Essentials of 3D biofabrication and …, 2015 - Elsevier
Extrusion bioprinting has exciting prospects in fabricating organized tissue constructs by
simultaneous dispensing of cells and matrix materials to repair or replace damaged or …