Background Anti‐integrin antibodies are effective therapies for Crohn's disease (CD) and
ulcerative colitis (UC). However, these drugs carry theoretical risks of opportunistic infection …

Background Evidence synthesis has seen major methodological advances in reducing
uncertainty and estimating the sizes of the effects. Much less is known about how to assess …

Singapore is in the midst of several healthcare reforms in efforts to finance and deliver
health services for a rapidly aging population. The primary focus of these reforms is to make …

Objectives: Biomarkers, endoscopy and imaging tests can identify patients at increased risk
for early recurrence of symptomatic inflammatory bowel disease (IBD). However, patients …

Objective The objective of this study was to identify, document, and weight attributes of a
pain medication that are relevant from the perspective of patients with chronic pain. Within …

Background Meningococcal disease is rare but can cause death or disabilities. Although the
Advisory Committee on Immunization Practices has recommended meningococcal …

Background: Previous studies suggest that efficacy is more important than side-effect risks to
psoriasis patients. However, those studies did not consider potentially fatal risks of biologic …

Background. While choices about genetic testing are increasingly common for patients and
families, and public opinion surveys suggest public interest in genomics, it is not known how …

The comparative evaluation of benefits and risks is one of the most important tasks during
the development, market authorization and post-approval pharmacovigilance of medicinal …

Acknowledgements: Writing assistance was provided by Dr Allan Johnson, Medical Writing
Limited. Support: The symposium was jointly organised and funded by Abbvie. All authors …