Synthetic nanoparticles for vaccines and immunotherapy

DJ Irvine, MC Hanson, K Rakhra, T Tokatlian - Chemical reviews, 2015 - ACS Publications
The immune system plays a critical role in our health. No other component of human
physiology plays a decisive role in as diverse an array of maladies, from deadly diseases …

Size selectivity of intestinal mucus to diffusing particulates is dependent on surface chemistry and exposure to lipids

HM Yildiz, CA McKelvey, PJ Marsac… - Journal of drug …, 2015 - Taylor & Francis
Intestinal mucus provides a significant barrier to transport of orally delivered drug carriers, as
well as other particulates (eg food, microbes). The relative significance of particle size …

Surface charge effect on mucoadhesion of chitosan based nanogels for local anti-colorectal cancer drug delivery

C Feng, J Li, M Kong, Y Liu, XJ Cheng, Y Li… - Colloids and Surfaces B …, 2015 - Elsevier
To develop more effective anticancer mucoadhesive drug delivery system for the treatment
of colorectal cancer, chitosan based nanogels (NGs) were prepared by electrostatic …

Modulating Vibrio cholerae Quorum-Sensing-Controlled Communication Using Autoinducer-Loaded Nanoparticles

HD Lu, AC Spiegel, A Hurley, LJ Perez, K Maisel… - Nano …, 2015 - ACS Publications
The rise of bacterial antibiotic resistance has created a demand for alternatives to traditional
antibiotics. Attractive possibilities include pro-and anti-quorum sensing therapies that …

Enema ion compositions for enhancing colorectal drug delivery

K Maisel, S Chattopadhyay, T Moench… - Journal of Controlled …, 2015 - Elsevier
Delivering drugs to the colorectum by enema has advantages for treating or preventing both
local and systemic diseases. However, the properties of the enema itself are not typically …

IBD Modern Concepts, Nano Drug Delivery and Patents: An Update

J Kumar, A Maria John Newton - Recent Patents on …, 2015 - ingentaconnect.com
IBD significantly affects the young population around the globe as the statistical reports
worldwide showing the threatening growth in the IBD individuals and patients. The etiology …