The search for specificity in cancers has been a holy grail in cancer immunology. Cancer
geneticists have long known that cancers harbor transforming and other mutations …

Heat shock proteins hsp70 and gp96 have been confirmed as adjuvants enabling induction
of cell-and antibody-mediated immunity specific to associated protein or peptide antigens …

Background Exosomes secreted by tumor cells contain specific antigens that may have
immunotherapeutic purposes. The aim of this study was to characterize the proteomic …

CD91 is a scavenger receptor expressed by different immune cells and its ligands defensins
have been demonstrated to contribute to immune responses against infections and tumours …

Purpose: To detect the expression and prognostic clinical significance of heat-shock protein
gp96 (HSP gp96) in gallbladder cancer. Methods: Immunohistochemistry was used to detect …

Hepatocellular carcinoma (HCC) is one of the most common malignancies over the world.
Alpha-fetoprotein (AFP) is an oncofetal protein during HCC development, which could …

The manuscript by Fong et al (2015) in this issue of The EMBO Journal addresses an
ongoing question in immunology: are extracellular HSP s endogenous inflammatory signals …

Diverse environmental and physiological factors are known to induce the transcription of a
set of genes encoding special protective molecules known as “molecular chaperones” within …

The immune system has huge potential in cancer treatment as it is individualized; exactness
driven and powerful, notwithstanding, it is related with difficulties of its own that incorporate …