BACKGROUND Neurodevelopmental disorders are caused by abnormalities in the
developing brain. Such abnormalities can occur as a result of germline or somatic mutations …

We provide an overview of recent progress on the study of astrocyte intracellular Ca2+
signaling. We consider the methods that have been used to monitor astrocyte Ca2+ signals …

Enhanced neuronal activity in the brain triggers a local increase in blood flow, termed
functional hyperemia, via several mechanisms, including calcium (Ca2+) signaling in …

Neuroglia, the “glue” that fills the space between neurons in the central nervous system,
takes active part in nerve cell signaling. Neuroglial cells, astroglia, oligodendroglia, and …

Recent breakthroughs in neuroscience have led to the awareness that we should revise our
traditional mode of thinking and studying the CNS, ie by isolating the privileged network of …

The mechanisms that link a transient neural activity to the corresponding increase of
cerebral blood flow (CBF) are termed neurovascular coupling (NVC). They are possibly …

Work over the past 20 years has implicated electrically nonexcitable astrocytes in complex
neural functions. Despite controversies, it is increasingly clear that many, if not all, neural …

According to the current model of neurovascular coupling, blood flow is controlled regionally
through phasic changes in the activity of neurons and astrocytes that signal to alter arteriole …

Alzheimer's disease (AD) is a progressive brain disorder that initially affects medial temporal
lobe circuitry and memory functions. Current drug treatments have only modest effects on …

Previous findings have shown that individuals with autism spectrum disorder (ASD) evince
greater intra-individual variability (IIV) in their sensory-evoked fMRI responses compared to …