[HTML][HTML] Synchronization of biological clock neurons by light and peripheral feedback systems promotes circadian rhythms and health

A Ramkisoensing, JH Meijer - Frontiers in neurology, 2015 - frontiersin.org
In mammals, the suprachiasmatic nucleus (SCN) functions as a circadian clock that drives
24-h rhythms in both physiology and behavior. The SCN is a multicellular oscillator in which …

[HTML][HTML] Lipids around the clock: focus on circadian rhythms and lipid metabolism

D Gnocchi, M Pedrelli, E Hurt-Camejo, P Parini - Biology, 2015 - mdpi.com
Disorders of lipid and lipoprotein metabolism and transport are responsible for the
development of a large spectrum of pathologies, ranging from cardiovascular diseases, to …

[HTML][HTML] Smooth-muscle BMAL1 participates in blood pressure circadian rhythm regulation

Z Xie, W Su, S Liu, G Zhao, K Esser… - The Journal of …, 2015 - Am Soc Clin Investig
As the central pacemaker, the suprachiasmatic nucleus (SCN) has long been considered
the primary regulator of blood pressure circadian rhythm; however, this dogma has been …

Variations in phase and amplitude of rhythmic clock gene expression across prefrontal cortex, hippocampus, amygdala, and hypothalamic paraventricular and …

LE Chun, ER Woodruff, S Morton… - Journal of biological …, 2015 - journals.sagepub.com
The molecular circadian clock is a self-regulating transcription/translation cycle of positive
(Bmal1, Clock/Npas2) and negative (Per1, 2, 3, Cry1, 2) regulatory components. While the …

Maternal Ube3a loss disrupts sleep homeostasis but leaves circadian rhythmicity largely intact

JC Ehlen, KA Jones, L Pinckney, CL Gray… - Journal of …, 2015 - Soc Neuroscience
Individuals with Angelman syndrome (AS) suffer sleep disturbances that severely impair
quality of life. Whether these disturbances arise from sleep or circadian clock dysfunction is …

Skeletal muscle functions around the clock

A Mayeuf‐Louchart, B Staels… - Diabetes, obesity and …, 2015 - Wiley Online Library
In mammals, the central clock localized in the central nervous system imposes a circadian
rhythmicity to all organs. This is achieved thanks to a well‐conserved molecular clockwork …

[HTML][HTML] A tunable artificial circadian clock in clock-defective mice

M D'Alessandro, S Beesley, JK Kim, R Chen… - Nature …, 2015 - nature.com
Self-sustaining oscillations are essential for diverse physiological functions such as the cell
cycle, insulin secretion and circadian rhythms. Synthetic oscillators using biochemical …

Diurnal oscillation of amygdala clock gene expression and loss of synchrony in a mouse model of depression

G Savalli, W Diao, S Schulz, K Todtova… - International Journal of …, 2015 - academic.oup.com
Background: Disturbances in circadian rhythm-related physiological and behavioral
processes are frequently observed in depressed patients and several clock genes have …

Acute morphine affects the rat circadian clock via rhythms of phosphorylated ERK1/2 and GSK3β kinases and Per1 expression in the rat suprachiasmatic nucleus

D Pačesová, B Volfová, K Červená… - British journal of …, 2015 - Wiley Online Library
Background and Purpose Opioids affect the circadian clock and may change the timing of
many physiological processes. This study was undertaken to investigate the daily changes …

[HTML][HTML] Transcriptome analysis of food habit transition from carnivory to herbivory in a typical vertebrate herbivore, grass carp Ctenopharyngodon idella

S He, XF Liang, L Li, J Sun, ZY Wen, XY Cheng, AX Li… - BMC genomics, 2015 - Springer
Background Although feeding behavior and food habit are ecologically and economically
important properties, little is known about formation and evolution of herbivory. Grass carp …