Neurofibrillary tangles and amyloid plaques constitute the hallmark brain lesions of
Alzheimer's disease (AD) patients. Tangles are composed of fibrillar aggregates of the …

Accelerating Alzheimer's research through ‘natural’ animal m... : Current Opinion in Psychiatry
Accelerating Alzheimer's research through ‘natural’ animal models : Current Opinion in …

Alzheimer´ s disease (AD), a neurodegenerative illness involving synaptic dysfunction with
extracellular accumulation of Aβ1-42 toxic peptide, glial activation, inflammatory response …

New studies show that the retina also undergoes pathological changes during the
development of Alzheimer's disease (AD). While transgenic mouse models used in these …

Alzheimer's disease (AD) is the most common form of neurodegenerative dementia
accounting for 50–80% of all age-related dementia. This pathology is characterized by the …

Alzheimer's disease (AD) is the most common neurodegenerative disorder and the leading
cause of age‐related dementia worldwide. Several models for AD have been developed to …

A variety of species express the amyloid β-protein (Aβ (the term “Aβ” refers both to Aβ40 and
Aβ42, whereas “Aβ40” and “Aβ42” refer to each isoform specifically). Those species …

Alzheimer's disease (AD) is the most common cause of dementia, affecting more than 36
million people worldwide. Octodon degus, a South American rodent, has been found to …

The benefits of neuromodulatory procedures as a possible therapeutic application for
cognitive rehabilitation have increased with the progress made in non-invasive modes of …

The retina is sensitive to age-dependent degeneration. To find suitable animal models to
understand and map this process has particular importance. The degu (Octodon degus) is a …