Macrophages are immune cells of haematopoietic origin that provide crucial innate immune
defence and have tissue-specific functions in the regulation and maintenance of organ …

Macrophages are myeloid immune cells that are strategically positioned throughout the
body tissues, where they ingest and degrade dead cells, debris, and foreign material and …

Microglia are the resident macrophages of the central nervous system (CNS), which sit in
close proximity to neural structures and are intimately involved in brain homeostasis. The …

During early embryogenesis, microglia arise from yolk sac progenitors that populate the
developing central nervous system (CNS), but how the tissue-resident macrophages are …

Microglia are macrophages that colonize the brain during development to establish a
resident population of professional phagocytes that protect against invading pathogens and …

Gliomas consist of multiple cell types, including an abundant number of microglia and
macrophages, whereby their impact on tumor progression is controversially discussed. To …

Microglia are considered the brain's resident immune cell involved in immune defense,
immunocompetence, and phagocytosis. They maintain tissue homeostasis within the brain …

Genetic targeting of microglia and other myeloid cells in the central nervous system (CNS) is
highly desirable as they are critical effectors and regulators of changes in CNS homeostasis …

Dopamine is the predominant catecholamine in the brain and functions as a
neurotransmitter. Dopamine is also a potent immune modulator. In this study, we have …

Abstract Mucopolysaccharidosis type II (MPS II) is a neuropathic lysosomal storage disorder
caused by a deficiency of iduronate-2-sulfatase (IDS), which leads to the accumulation of …