[HTML][HTML] Reactivating p53 functions by suppressing its novel inhibitor iASPP: a potential therapeutic opportunity in p53 wild-type tumors
P Dong, K Ihira, J Hamada, H Watari, T Yamada… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Although mutational inactivation of p53 is found in 50% of all human tumors, a subset of
tumors display defective p53 function, but retain wild-type (WT) p53. Here, direct and indirect …
tumors display defective p53 function, but retain wild-type (WT) p53. Here, direct and indirect …
MIR517C inhibits autophagy and the epithelial-to-mesenchymal (-like) transition phenotype in human glioblastoma through KPNA2-dependent disruption of TP53 …
Y Lu, L Xiao, Y Liu, H Wang, H Li, Q Zhou, J Pan… - Autophagy, 2015 - Taylor & Francis
The epithelial-to-mesenchymal (-like) transition (EMT), a crucial embryonic development
program, has been linked to the regulation of glioblastoma (GBM) progression and invasion …
program, has been linked to the regulation of glioblastoma (GBM) progression and invasion …
Expression of bcl-2 and p53 in bovine cutaneous fibropapillomas
Background Bovine cutaneous fibropapillomas are benign hyperproliferative lesions
induced by Bovine Papillomaviruses (BPVs). Bcl-2 is an important anti-apoptotic protein …
induced by Bovine Papillomaviruses (BPVs). Bcl-2 is an important anti-apoptotic protein …
Anticancer effect of a novel palladium–saccharinate complex of terpyridine by inducing apoptosis on Ehrlich ascites carcinoma (EAC) in Balb-C mice
EI Ikitimur-Armutak, K Sonmez, K Akgun-Dar… - Anticancer …, 2015 - ar.iiarjournals.org
Background/Aim:[Pd (sac)(terpy)](sac)• 4H2O (sac= saccharinate and terpy= 2, 2': 6', 2”-
terpyridine) is newly-synthesized palladium (II)(Pd) complex. We investigated the …
terpyridine) is newly-synthesized palladium (II)(Pd) complex. We investigated the …
Differentiation of human neuroblastoma cells toward the osteogenic lineage by mTOR inhibitor
A Carpentieri, E Cozzoli, M Scimeca, E Bonanno… - Cell Death & …, 2015 - nature.com
Current hypothesis suggest that tumors can originate from adult cells after a process
of'reprogramming'driven by genetic and epigenetic alterations. These cancer cells, called …
of'reprogramming'driven by genetic and epigenetic alterations. These cancer cells, called …
Neoplasia diseminada en poblaciones del berberecho Cerastoderma edule en Galicia
SM Díaz Costas - minerva.usc.es
El berberecho Cerastoderma edule es una especie de gran interés comercial en Galicia. Es
una de las especies de bivalvo con más capturas anuales y por lo tanto tiene una elevada …
una de las especies de bivalvo con más capturas anuales y por lo tanto tiene una elevada …
[PDF][PDF] " Influence of MAGEA and effects of resveratrol on p53 biology
B Demoulin - 2015 - core.ac.uk
MAGEA1 and-A2 impair the stabilization and activation of p53 in presence of a genotoxic
stress. MAGEA (Melanoma AntiGEn-A) genes are silenced in the vast majority of healthy …
stress. MAGEA (Melanoma AntiGEn-A) genes are silenced in the vast majority of healthy …
Expression of bcl-2 and p53 in bovine cutaneous fibropapillomas
Background Bovine cutaneous fibropapillomas are benign hyperproliferative lesions
induced by Bovine Papillomaviruses (BPVs). Bcl-2 is an important anti-apoptotic protein …
induced by Bovine Papillomaviruses (BPVs). Bcl-2 is an important anti-apoptotic protein …
p53 at the Crossroads Between Stress Response Signaling and Tumorigenesis: From Molecular Mechanisms to Therapeutic Opportunities
LE Giono, MF Ladelfa, M Monte - … in Cancer: From Molecular Targets to …, 2015 - Springer
The p53 tumor suppressor is a transcription factor that integrates signals from numerous
stress-activated signaling pathways and regulates the expression of specific target genes …
stress-activated signaling pathways and regulates the expression of specific target genes …