Throughout the last decade, increasing awareness has been raised on issues related to
reproduction in rheumatic diseases including basic research to clarify the important role of …

For patients with antiphospholipid syndrome (APS), the consensus is to treat those who
develop thrombosis with long-term oral anticoagulation therapy and to prevent obstetric …

Objectives To assess the prevalence of the main causes of morbi-mortality in the
antiphospholipid syndrome (APS) during a 10-year-follow-up period and to compare the …

We performed an individual patient meta-analysis to determine whether aspirin has a
significant protective effect on the risk of first thrombosis among patients with …

Accurate diagnosis of obstetric antiphospholipid syndrome (APS) is a prerequisite for
optimal clinical management. The international consensus (revised Sapporo) criteria for …

Abstract Systemic Lupus Erythematosus (SLE) is an acquired, multiorgan, autoimmune
disease. Clinical presentation is extremely variable and heterogeneous. It has been shown …

Vascular thrombosis and pregnancy morbidity represent the clinical manifestations of
antiphospholipid syndrome (APS), which is serologically characterized by the persistent …

Catastrophic thrombotic syndromes are characterized by rapid onset of multiple
thromboembolic occlusions affecting diverse vascular beds. Patients may have multiple …

Data on the clinical course of lupus anticoagulant (LA)–positive individuals with or without
thrombotic manifestations or pregnancy complications are limited. To investigate mortality …

Introduction In antiphospholipid syndrome (APS), certain principal manifestations are
associated with a worse prognosis and organ damage. Objective The objective of this paper …