Introduction: Opioid overdose fatality has increased threefold since 1999. As a result,
prescription drug overdose surpassed motor vehicle collision as the leading cause of …

Opioid overdose is reversible through the timely administration of naloxone, which has been
used by emergency medical services for decades. Law enforcement officers (LEOs) are …

Background Opioid overdose, which has reached epidemic levels in the United States, is
reversible by administration of the medication naloxone. Naloxone requires a prescription …

Aims To describe characteristics of participants and overdose reversals associated with a
community‐based naloxone distribution program and identify predictors of obtaining …

疼痛是组织损伤或潜在的组织损伤引起的不愉快的感觉或情绪的体验, 慢性疼痛是一个全球性
难题. 全球成人中约20%(1.2 亿) 患有慢性疼痛. 并且, 每年约有10%(6000 万) 的新增病例. 其中 …

As pediatric imaging capabilities have increased in scope, so have the complexities of
providing procedural sedation in this environment. While efforts by many organizations have …

Opioid antagonists are pharmacological tools applied as an indirect measure to detect
activation of the endogenous opioid system (EOS) in experimental pain models. The …

Background Central sensitization is modulated by the endogenous opioid system and plays
a major role in the development and maintenance of pain. Recent animal studies performed …

Since its inception in 2010, the Network for Public Health Law (Network) has aligned with
federal, state, tribal, and local public health practitioners to assess how law can promote and …

Opioid withdrawal in the pediatric patient and opioid use disorder, intoxication, withdrawal,
and treatment in adults are discussed separately.(See" Prenatal substance exposure and …