Accessorizing and anchoring the LINC complex for multifunctionality
W Chang, HJ Worman, GG Gundersen - Journal of Cell Biology, 2015 - rupress.org
The linker of nucleoskeleton and cytoskeleton (LINC) complex, composed of outer and inner
nuclear membrane Klarsicht, ANC-1, and Syne homology (KASH) and Sad1 and UNC-84 …
nuclear membrane Klarsicht, ANC-1, and Syne homology (KASH) and Sad1 and UNC-84 …
Making the LINC: SUN and KASH protein interactions
Cell nuclei are physically integrated with the cytoskeleton through the linker of
nucleoskeleton and cytoskeleton (LINC) complex, a structure that spans the nuclear …
nucleoskeleton and cytoskeleton (LINC) complex, a structure that spans the nuclear …
Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells
MH Wilson, ELF Holzbaur - Development, 2015 - journals.biologists.com
During skeletal muscle development, nuclei move dynamically through myotubes in a
microtubule-dependent manner, driven by the microtubule motor protein kinesin-1. Loss of …
microtubule-dependent manner, driven by the microtubule motor protein kinesin-1. Loss of …
[HTML][HTML] LINC'ing form and function at the nuclear envelope
P Meinke, EC Schirmer - FEBS letters, 2015 - Elsevier
The nuclear envelope is an amazing piece of engineering. On one hand it is built like a
mediaeval fortress with filament systems reinforcing its membrane walls and its double …
mediaeval fortress with filament systems reinforcing its membrane walls and its double …
Do lamin A and lamin C have unique roles?
R Al-Saaidi, P Bross - Chromosoma, 2015 - Springer
The A-type lamins, lamin A and lamin C, generated from a single gene, LMNA, are major
structural components of the nuclear lamina. The two alternative splice products have mostly …
structural components of the nuclear lamina. The two alternative splice products have mostly …
[HTML][HTML] Nesprin‑1 has key roles in the process of mesenchymal stem cell differentiation into cardiomyocyte‑like cells in vivo and in vitro
W Yang, H Zheng, Y Wang… - Molecular medicine …, 2015 - spandidos-publications.com
The aim of the present study was to investigate the expression of nesprin‑1 protein in MSCs
and its effects on the differentiation of rat bone‑marrow mesenchymal stem cells (MSCs) …
and its effects on the differentiation of rat bone‑marrow mesenchymal stem cells (MSCs) …
Inner nuclear membrane protein LEM-2 is required for correct nuclear separation and morphology in C. elegans
A Morales-Martínez, A Dobrzynska… - Journal of cell …, 2015 - journals.biologists.com
The inner nuclear membrane proteins emerin and LEMD2 have both overlapping and
separate functions in regulation of nuclear organization, gene expression and cell …
separate functions in regulation of nuclear organization, gene expression and cell …
[PDF][PDF] Nucleus to synapse Nesprin1 railroad tracks direct synapse maturation through RNA localization
An important mechanism underlying synapse development and plasticity is the localization
of mRNAs that travel from the nucleus to synaptic sites. Here we demonstrate that the giant …
of mRNAs that travel from the nucleus to synaptic sites. Here we demonstrate that the giant …
Role of structural flexibility in the evolution of emerin
J Yuan, B Xue - Journal of Theoretical Biology, 2015 - Elsevier
Emerin is a short inner nuclear membrane protein with an LEM-domain at the N-terminal
end and a transmembrane domain at the C-terminal end. The middle region of human …
end and a transmembrane domain at the C-terminal end. The middle region of human …
[PDF][PDF] Клинико-генетическое разнообразие и молекулярная диагностика мышечной дистрофии Эмери–Дрейфуса
ТА Адян - 2015 - med-gen.ru
Мышечная дистрофия Эмери–Дрейфуса (МД ЭД)–генетически гетерогенная группа
болезней, характеризующихся триадой типичных симптомов: первичными …
болезней, характеризующихся триадой типичных симптомов: первичными …