Rheumatoid arthritis (RA) is considered a chronic disease that cannot be cured. Biologic
agents have enabled good therapeutic successes; however, the response to biologic …

The human immune system involves highly complex and coordinated processes in which
small proteins named cytokines play a key role. Cytokines have been implicated in the …

Objective To evaluate the efficacy and safety of sarilumab in combination with methotrexate
(MTX) for the treatment of rheumatoid arthritis (RA). Methods Adults with moderate‐to …

Purpose To evaluate the reliability and validity of 11 PROMIS measures to assess symptoms
and impacts identified as important by people with rheumatoid arthritis (RA). Methods …

Background Disease-modifying biological agents and other drug regimens have
substantially improved control of disease activity and joint damage in people with …

BACKGROUND: Given the availability of a number of alternative biologic treatment options
and other novel disease-modifying antirheumatic drugs (DMARDs) for the treatment of …

There is a growing interest in patient-reported outcomes (PROs) in rheumatology, which
goes with a global trend for more 'patient-centred care'. This review considers the use of …

Objective Clazakizumab is a humanized monoclonal antibody that binds to the interleukin‐6
(IL‐6) cytokine. This study was undertaken to evaluate the efficacy and safety of …

Patient reported outcomes (PRO) are at the core of assessing RA treatment response with
patient assessments of global health or disease activity, pain, and physical function included …

Background Standing balance is imperative for mobility and avoiding falls. Use of an
excessive number of standing balance measures has limited the synthesis of balance …