Diabetic cardiomyopathy (DCM) is a common consequence of longstanding type 2 diabetes
mellitus (T2DM) and encompasses structural, morphological, functional, and metabolic …

In addition to established membrane remodeling roles in various cellular locations, actin has
recently emerged as a participant in mitochondrial fission. However, the underlying …

Diminished glucose metabolism accompanies many neurodegenerative diseases including
Alzheimer's disease. An understanding of the relation of these metabolic changes to the …

Background Dysfunction of mitochondria is involved in podocyte injury in some kidney
diseases, but the relationship between abnormal mitochondrial morphology and podocyte …

The emerging evidences suggest that posttranslational modification of target protein by
ubiquitin (Ub) not only regulate its turnover through ubiquitin proteasome system (UPS) but …

Mitochondrial function is influenced by alterations in oncogenes and tumor suppressor
genes and changes in the microenvironment occurring during tumorigenesis. Therefore, we …

Mitochondrial (mt) genomes are intensively studied in Ascomycota and Basidiomycota, but
they are poorly documented in basal fungal lineages. In this study, we sequenced the …

Previous studies reported that a Gamitrinib variant containing triphenylphosphonium (G-
TPP) binds to mitochondrial Hsp90 and rapidly inhibits its activity to induce apoptosis. We …

Positive-strand RNA viruses amplify their genomes in membrane-bound structures
associated with intracellular membranes and organelles called replication complexes (RCs) …

Wnts are secreted morphogens that play pivotal roles in embryonic development, stem cell
biology and a number of disease states including cancer. Most Wnts signal through a …