Genetic and early environmental influences on the serotonin system: consequences for brain development and risk for psychopathology
Background: Despite more than 60 years of research in the role of serotonin (5-HT) in
psychopathology, many questions still remain. From a developmental perspective, studies …
psychopathology, many questions still remain. From a developmental perspective, studies …
Life without brain serotonin: reevaluation of serotonin function with mice deficient in brain serotonin synthesis
V Mosienko, D Beis, M Pasqualetti, J Waider… - Behavioural brain …, 2015 - Elsevier
Tryptophan hydroxylase (TPH) is a rate limiting enzyme in the synthesis of serotonin (5-HT),
a monoamine which works as an autacoid in the periphery and as a neurotransmitter in the …
a monoamine which works as an autacoid in the periphery and as a neurotransmitter in the …
Tryptophan hydroxylase 2 in seasonal affective disorder: underestimated perspectives?
AV Kulikov, NK Popova - Reviews in the Neurosciences, 2015 - degruyter.com
Seasonal affective disorder (SAD) is characterized by recurrent depression occurring
generally in fall/winter. Numerous pieces of evidence indicate the association of SAD with …
generally in fall/winter. Numerous pieces of evidence indicate the association of SAD with …
Serotonergic gene variation in substance use pharmacotherapy: a systematic review
IE Bauer, DP Graham, JC Soares… - Pharmacogenomics, 2015 - Taylor & Francis
Drug addiction is a serious disease with damaging effects on the brain and physical health.
Despite the increase in the number of affected individuals, there are few effective …
Despite the increase in the number of affected individuals, there are few effective …
Beyond gene inactivation: evolution of tools for analysis of serotonergic circuitry
C Hainer, V Mosienko, S Koutsikou… - ACS chemical …, 2015 - ACS Publications
In the brain, serotonin (5-hydroxytryptamine, 5-HT) controls a multitude of physiological and
behavioral functions. Serotonergic neurons in the raphe nuclei give rise to a complex and …
behavioral functions. Serotonergic neurons in the raphe nuclei give rise to a complex and …
[HTML][HTML] Genetic variations in the serotonergic system contribute to amygdala volume in humans
The amygdala plays a critical role in emotion processing and psychiatric disorders
associated with emotion dysfunction. Accumulating evidence suggests that amygdala …
associated with emotion dysfunction. Accumulating evidence suggests that amygdala …
[HTML][HTML] TPH2 variant rs7305115 and its interaction with acute stressful life events in etiology of suicide attempt in Serbian psychiatric patients
J Karanović, M Ivković, M Pantović… - Acta Medica …, 2015 - journals.lww.com
Methods: 165 suicide attempters and 188 suicide non-attempters, suffering from major
psychiatric disorders, participated in the study. Acute SLEs score was assessed using the …
psychiatric disorders, participated in the study. Acute SLEs score was assessed using the …