The first Ni0/bis (oxazoline)‐catalyzed asymmetric denitrogenative transannulation of 1, 2, 3‐
benzotriazin‐4 (3H)‐ones with bulky internal alkynes to form novel axially chiral …

The first catalytic intermolecular proximal C1 C2 cleavage of benzocyclobutenones (BCB)
without prior carbonyl activation or employing noble metals has been developed. This …

The catalytic asymmetric Michael addition/desymmetrization reaction of N-(2-t-butylphenyl)
maleimides with unprotected 3-substituted-2-oxindoles was successfully realized using a …

A Lewis acid catalyzed intramolecular [3+ 2] cross cycloaddition of cobalt-
alkynylcyclopropane 1, 1-diesters with carbonyls has been successfully developed …

A single-handed helical polymer ligand PQXphos afforded axially chiral biaryl esters with
high enantioselectivities in asymmetric Suzuki–Miyaura cross-coupling. The use of naphthyl …

Dibenzocyclooctadiene lignans represent a unique group of natural chemical structures, are
considered as protectants against neuronal cell death and cognitive impairment in …

A tandem isomerization/intramolecular [3+ 2] cross-cycloaddition (IMCC) of cyclopropane 1,
1-diesters with α, β-unsaturated ketones/aldehydes under a cooperative catalysis of photo …

Nordihydroguaiaretic acid (NDGA) is a natural polyphenol with a broad spectrum of
pharmacological properties. However, its usefulness is hindered by the lack of …

Background Due to resistance to all classes of anti-HIV drugs and drug toxicity, there is a
need for the discovery and development of new anti-HIV drugs. Methods HIV-1 inhibitors …

I would like to express my special appreciation and thanks to my supervisor Prof. Dulcie
Mulholland, who provided me with the opportunity to work within the interesting and diverse …