Isoniazid prophylactic therapy for the prevention of tuberculosis in HIV infected adults: a systematic review and meta-analysis of randomized trials

HT Ayele, MSM Mourik, TPA Debray, MJM Bonten - PloS one, 2015 - journals.plos.org
Background Infection with Human Immunodeficiency virus (HIV) is an important risk factor for
Tuberculosis (TB). Anti-Retroviral Therapy (ART) has improved the prognosis of HIV and …

A trial of early antiretrovirals and isoniazid preventive therapy in Africa

Temprano ANRS 12136 Study … - New England Journal of …, 2015 - Mass Medical Soc
Background In sub-Saharan Africa, the burden of human immunodeficiency virus (HIV)–
associated tuberculosis is high. We conducted a trial with a 2-by-2 factorial design to assess …

Non-tuberculous mycobacteria in children: muddying the waters of tuberculosis diagnosis

E López-Varela, AL García-Basteiro… - The Lancet …, 2015 - thelancet.com
Non-tuberculous mycobacteria (NTM) are a large family of acid-fast bacteria, widespread in
the environment. In children, NTM cause lymphadenitis, skin and soft tissue infections, and …

Tuberculosis incidence after 36 months' isoniazid prophylaxis in HIV-infected adults in Botswana: a posttrial observational analysis

T Samandari, TB Agizew, S Nyirenda, Z Tedla… - Aids, 2015 - journals.lww.com
Objective: Thirty-six months of isoniazid preventive therapy (36IPT) was superior to 6 months
of IPT (6IPT) in preventing tuberculosis (TB) among HIV-infected adults in Botswana. We …

Prevalence and determinants of Tuberculosis among HIV infected patients in south Ethiopia

S Fekadu, W Teshome, G Alemu - The Journal of Infection in Developing …, 2015 - jidc.org
Introduction: Tuberculosis (TB) is a chronic infectious disease that has represented a major
health problem over the centuries. The human immune deficiency virus (HIV)/AIDS has …

The impact of HIV status and antiretroviral treatment on TB treatment outcomes of new tuberculosis patients attending co-located TB and ART services in South Africa …

MD Nglazi, LG Bekker, R Wood, R Kaplan - BMC infectious diseases, 2015 - Springer
Background The implementation of collaborative TB-HIV services is challenging. We,
therefore, assessed TB treatment outcomes in relation to HIV infection and antiretroviral …

High tuberculosis burden among people living with HIV in southern Mozambique

AL García-Basteiro, E López-Varela… - European …, 2015 - Eur Respiratory Soc
Tuberculosis (TB) remains an important public health concern, and a leading cause of
disease and death worldwide. Mozambique is one of the few high TB burden countries …

Does antiretroviral therapy reduce HIV-associated tuberculosis incidence to background rates? A national observational cohort study from England, Wales, and …

RK Gupta, B Rice, AE Brown, HL Thomas, D Zenner… - The lancet HIV, 2015 - thelancet.com
Background Whether the incidence of tuberculosis in HIV-positive people receiving long-
term antiretroviral therapy (ART) remains above background population rates is unclear. We …

Tuberculosis incidence and risk factors among human immunodeficiency virus (HIV)-infected adults receiving antiretroviral therapy in a large HIV program in Nigeria

CA Chang, ST Meloni, G Eisen… - Open forum …, 2015 - academic.oup.com
Background. Despite the benefits of antiretroviral therapy (ART), tuberculosis (TB) is the
leading cause of mortality among human immunodeficiency virus (HIV)-infected persons in …

Persistent high mortality in advanced HIV/TB despite appropriate antiretroviral and antitubercular therapy: an emerging challenge

GP Bisson, N Zetola, RG Collman - Current HIV/AIDS Reports, 2015 - Springer
Abstract Approximately 1.1 million, or 13%, of all TB cases in 2013 were coinfected with HIV,
and in some African countries, such as Botswana and Swaziland, 60–80% of TB cases are …