Background Chronic sinonasal disease is common in asthmatic patients and associated
with poor asthma control; however, there are no long-term trials addressing whether chronic …

Three quarters of all critical incidents and a third of all peri‐operative cardiac arrests in
paediatric anaesthesia are caused by adverse respiratory events. We screened for risk …

Background Nasal inflammation in allergic rhinitis enhances bronchial Th2 driven
inflammation and development of asthma. We assessed bronchial inflammation induced by …

Purpose Extensive data support the influence of the upper airway on lower airway
inflammation and pathophysiology in allergic disease. However, few studies have focused …

Background Despite the well-known association between asthma and rhinitis, in Swedish
adults the prevalence of rhinitis rose from 22% to 31% between 1990 and 2008 while …

Throughout 2014, notable publications in the Annals covered unique and important aspects
of the upper respiratory tract. The International Study of Asthma and Allergies in Childhood …

Back ground: Allergic diseases are group of diseases which are very common in population
and occur in all ages. Aim: for determination of allergic diseases in albasrah population …

Purpose: Extensive data support the influence of the upper airway on lower airway
inflammation and pathophysiology in allergic disease. However, few studies have focused …

Airway inflammation with eosinophils as well as CD4+ T cells is a characteristic feature of
asthma and is considered relevant to the pathogenesis of the disease (1). Allergen …

Background The Allergic Rhinitis Clinical Investigator Collaborative (AR-CIC) uses a Nasal
Allergen Challenge (NAC) model to study the pathophysiology of AR and provides proof of …