hmmSeq: A hidden Markov model for detecting differentially expressed genes from RNA-seq data

S Cui, S Guha, MAR Ferreira, AN Tegge - 2015 - projecteuclid.org
hmmSeq: A hidden Markov model for detecting differentially expressed genes from RNA-seq
data Page 1 The Annals of Applied Statistics 2015, Vol. 9, No. 2, 901–925 DOI: 10.1214/15-AOAS815 …

Modeling the next generation sequencing read count data for DNA copy number variant study

T Ji, J Chen - Statistical applications in genetics and molecular …, 2015 - degruyter.com
As one of the most recent advanced technologies developed for biomedical research, the
next generation sequencing (NGS) technology has opened more opportunities for scientific …

[PDF][PDF] Clinical and genomic strategies for detecting hepatocellular carcinoma in early stages: a systematic review

EM Hashem, MS Mabrouk, AM Eldeib - Am J Biomed Eng, 2015 - researchgate.net
Hepatocellular carcinoma is one of the commonest deadly tumors, and it is usually diagnose
at a late stage, when effective treatment is very difficult. Making its discovery before the …

An online copy number variant detection method for short sequencing reads

A Yiğiter, J Chen, L An… - Journal of Applied Statistics, 2015 - Taylor & Francis
The availability of the next generation sequencing (NGS) technology in today's biomedical
research has provided new opportunities in scientific discovery of genetic information. The …

A Bayesian Analysis of Copy Number Variations in Array Comparative Genomic Hybridization Data

X Wu, H Zhu - 2015 - vtechworks.lib.vt.edu
Abstract Array Comparative Genomic Hybridization (CGH) has been widely used for
detecting genomic copy number variations (CNVs). The central goal of array CGH data …

Species sampling priors for modeling dependence: an application to the detection of chromosomal aberrations

F Bassetti, F Leisen, E Airoldi, M Guindani - … Bayesian Inference in …, 2015 - Springer
We discuss a class of Bayesian nonparametric priors that can be used to model local
dependence in a sequence of observations. Many popular Bayesian nonparametric priors …

Optimization of signal decomposition matched filtering (SDMF) for improved detection of copy-number variations

C Stamoulis, RA Betensky - IEEE/ACM Transactions on …, 2015 - ieeexplore.ieee.org
We aim to improve the performance of the previously proposed signal decomposition
matched filtering (SDMF) method [26] for the detection of copy-number variations (CNV) in …

[PDF][PDF] A stochastic segmentation model for recurrent copy number alteration analysis

H Xing, Y Cai - Journal of Biometrics & Biostatistics, 2015 - ams.stonybrook.edu
Recurrent DNA copy number alterations (CNAs) are key genetic events in the study of
human genetics and disease. Analysis of recurrent DNA CNA data often involves the …

[PDF][PDF] Change-point estimation in piecewise constant regression models and extensions

S FASOLA - 2015 - iris.unipa.it
1.1 Background The problem of change-point detection appears to have been introduced in
the quality control context (Shewhart, 1925), where it was concerned with the monitoring of …