Prognostic significance of dynamic 18F-FET PET in newly diagnosed astrocytic high-grade glioma
NL Jansen, B Suchorska, V Wenter… - Journal of Nuclear …, 2015 - Soc Nuclear Med
Despite advances in diagnosis and the use of different therapeutic regimens in astrocytic
high-grade glioma (HGG), the prognosis for patients remains grim. Additional pretherapeutic …
high-grade glioma (HGG), the prognosis for patients remains grim. Additional pretherapeutic …
Dynamic 18F‐FET PET in suspected WHO grade II gliomas defines distinct biological subgroups with different clinical courses
N Thon, M Kunz, L Lemke, NL Jansen… - … journal of cancer, 2015 - Wiley Online Library
In suspected grade II gliomas, three distinct patterns of time–activity curves (TAC) on O‐(2‐
[18F] fluoroethyl)‐1‐tyrosine (18F‐FET) positron emission tomography (PET) have been …
[18F] fluoroethyl)‐1‐tyrosine (18F‐FET) positron emission tomography (PET) have been …
18F-fluoro-ethyl-tyrosine positron emission tomography for grading and estimation of prognosis in patients with intracranial gliomas
J Gempt, S Bette, YM Ryang, N Buchmann… - European journal of …, 2015 - Elsevier
Introduction Histopathological examination is the standard for grading and determination of
diagnosis in intrinsic brain tumors though the possibility of malignization and tumor …
diagnosis in intrinsic brain tumors though the possibility of malignization and tumor …
Loss of 5-hydroxymethylcytosine and intratumoral heterogeneity as an epigenomic hallmark of glioblastoma
TFJ Kraus, G Kolck, A Greiner, K Schierl, V Guibourt… - Tumor Biology, 2015 - Springer
Glioblastoma (GBM) is the most malignant neoplasm with predominant astrocytic
differentiation and the most frequent primary brain tumor of the adult. Here, we investigated …
differentiation and the most frequent primary brain tumor of the adult. Here, we investigated …
The role of surgery in grade II/III oligodendroglial tumors
N Thon, FW Kreth, JC Tonn - CNS oncology, 2015 - Taylor & Francis
Supratentorial gliomas WHO grade II and III with an oligodendroglial phenotype are highly
infiltrative lesions that preferentially originate in lobar location. Open tumor resection …
infiltrative lesions that preferentially originate in lobar location. Open tumor resection …
18F-Fluorodeoxyglucose and 11C-methionine positron emission tomography in relation to methyl-guanine methyltransferase promoter methylation in high-grade …
Results Maximum TNR FDG of the MGMT methylated group was significantly higher than
that of the MGMT unmethylated group (1.80±0.90 vs. 1.29±0.19; P= 0.02). The MGMT …
that of the MGMT unmethylated group (1.80±0.90 vs. 1.29±0.19; P= 0.02). The MGMT …