The immunogenetics of psoriasis: a comprehensive review

JL Harden, JG Krueger, AM Bowcock - Journal of autoimmunity, 2015 - Elsevier
Psoriasis vulgaris is a common, chronic inflammatory skin disease with a complex etiology
involving genetic risk factors and environmental triggers. Here we describe the many known …

Psoriasis: classical and emerging comorbidities

MFSP Oliveira, BO Rocha, GV Duarte - Anais brasileiros de …, 2015 - SciELO Brasil
Psoriasis is a chronic inflammatory systemic disease. Evidence shows an association of
psoriasis with arthritis, depression, inflammatory bowel disease and cardiovascular …

Psoriasis is a systemic disease with multiple cardiovascular and metabolic comorbidities

C Ryan, B Kirby - Dermatologic clinics, 2015 - derm.theclinics.com
Once considered to be solely a cutaneous disease, there is now robust evidence that
psoriasis is associated with systemic inflammation and a significantly increased risk of …

The translational revolution and use of biologics in patients with inflammatory skin diseases

S Noda, JG Krueger, E Guttman-Yassky - Journal of Allergy and Clinical …, 2015 - Elsevier
Psoriasis and atopic dermatitis (AD) are common inflammatory skin diseases characterized
by immune-mediated inflammation and abnormal keratinocyte differentiation. Although T …

Adiponectin regulates psoriasiform skin inflammation by suppressing IL-17 production from γδ-T cells

S Shibata, Y Tada, CS Hau, A Mitsui, M Kamata… - Nature …, 2015 - nature.com
Accumulating epidemiologic evidence has revealed that metabolic syndrome is an
independent risk factor for psoriasis development and is associated with more severe …

Obesity is associated with a lower probability of achieving sustained minimal disease activity state among patients with psoriatic arthritis

L Eder, A Thavaneswaran, V Chandran… - Annals of the …, 2015 - ard.bmj.com
Aim To assess whether overweight and obese patients with psoriatic arthritis (PsA) are less
likely to achieve sustained minimal disease activity (MDA) state compared to patients with …

Insulin resistance and skin diseases

M Napolitano, M Megna… - The Scientific World …, 2015 - Wiley Online Library
In medical practice, almost every clinician may encounter patients with skin disease.
However, it is not always easy for physicians of all specialties to face the daily task of …

Dermal IL‐17‐producing γδ T cells establish long‐lived memory in the skin

T Hartwig, S Pantelyushin, AL Croxford… - European journal of …, 2015 - Wiley Online Library
Conventional αβ T cells have the ability to form a long‐lasting resident memory T‐cell (TRM)
population in nonlymphoid tissues after encountering foreign antigen. Conversely, the …

[PDF][PDF] Cardiovascular risk profile at the onset of psoriatic arthritis: a population‐based cohort study

FC Ernste, M Sánchez‐Menéndez… - Arthritis care & …, 2015 - Wiley Online Library
Objective The role of cardiovascular disease (CVD) risk factors in psoriatic arthritis (PsA) is
poorly understood. We examined the prevalence of CVD risk factors at initial onset of PsA …

Association of chronic periodontitis and psoriasis: periodontal status with severity of psoriasis

A Sharma, A Raman, AR Pradeep - Oral Diseases, 2015 - Wiley Online Library
Objectives The chronic periodontitis (CP) and psoriasis share common risk factors and co‐
morbidities. This study was designed to explore how frequently CP is associated with …