BACKGROUND: COPD is a major cause of morbidity and mortality in the United States as
well as throughout the rest of the world. An exacerbation of COPD (periodic escalations of …

Chronic obstructive pulmonary disease (COPD) is a progressive and debilitating respiratory
condition that leads to significant burden, both medically and financially. It affects millions of …

COPD is a long-term condition associated with considerable disability with a clinical course
characterized by episodes of worsening respiratory signs and symptoms associated with …

Rationale: Exacerbations are important and heterogeneous events in the natural history of
chronic obstructive pulmonary disease (COPD). Objectives: To examine the consequences …

Background Chronic obstructive pulmonary disease (COPD) is a clinical syndrome
encompassing a group of chronic, progressive, and debilitating respiratory conditions, that …

Background The combination of aclidinium bromide, a long-acting anticholinergic, and
formoterol fumarate, a long-acting beta 2-agonist (400/12 μg twice daily) achieves …

Background The hallmark of non-cystic fibrosis bronchiectasis is recurrent bronchial
infection, yet there are significant gaps in our understanding of pathogen persistence …

Background The use of telehealth technologies to remotely monitor patients suffering
chronic diseases may enable preemptive treatment of worsening health conditions before a …

Rationale: Hospitalization represents a major event for the patient with chronic respiratory
disease. There is a high risk of readmission, which over the longer term may be related more …

SETTING: Clinical phenotypes of chronic obstructive pulmonary disease (COPD) identify
patients with common characteristics. OBJECTIVES: To investigate the distribution of four …