Markers of inflammation associated with plaque progression and instability in patients with carotid atherosclerosis
Atherosclerosis is the focal expression of a systemic disease affecting medium‐and large‐
sized arteries, in which traditional cardiovascular risk factor and immune factors play a key …
sized arteries, in which traditional cardiovascular risk factor and immune factors play a key …
Novel anti-inflammatory therapies for the treatment of atherosclerosis
R Khan, V Spagnoli, JC Tardif, PL L'Allier - Atherosclerosis, 2015 - Elsevier
The underlying role of inflammation in atherosclerosis has been characterized. However,
current treatment of coronary artery disease (CAD) predominantly consists of targeted …
current treatment of coronary artery disease (CAD) predominantly consists of targeted …
Proof that lower is better—LDL cholesterol and IMPROVE-IT
JA Jarcho, JF Keaney Jr - New England Journal of Medicine, 2015 - Mass Medical Soc
The so-called LDL hypothesis is the concept that excess low-density lipoprotein (LDL)
cholesterol is a causal factor in the development of atherosclerotic vascular disease. By …
cholesterol is a causal factor in the development of atherosclerotic vascular disease. By …
Cardiovascular risk assessment: a global perspective
D Zhao, J Liu, W Xie, Y Qi - Nature Reviews Cardiology, 2015 - nature.com
An important strategy in primary prevention of cardiovascular diseases (CVD) is the early
identification of high-risk individuals. Effective implementation of a strategy to identify these …
identification of high-risk individuals. Effective implementation of a strategy to identify these …
Reverse epidemiology of traditional cardiovascular risk factors in the geriatric population
Traditional risk factors of cardiovascular death in the general population, including body
mass index (BMI), serum cholesterol, and blood pressure (BP), are also found to relate to …
mass index (BMI), serum cholesterol, and blood pressure (BP), are also found to relate to …
Statin use and exacerbations in individuals with chronic obstructive pulmonary disease
TS Ingebrigtsen, JL Marott, BG Nordestgaard, P Lange… - Thorax, 2015 - thorax.bmj.com
Background We tested the hypothesis that statin use in individuals with COPD is associated
with a reduced risk of exacerbations. Methods We identified 5794 individuals with COPD …
with a reduced risk of exacerbations. Methods We identified 5794 individuals with COPD …
suPAR: a new biomarker for cardiovascular disease?
GW Hodges, CN Bang, K Wachtell… - Canadian Journal of …, 2015 - Elsevier
The fundamental role of inflammation in cardiovascular disease (CVD) has prompted
interest in numerous biomarkers that detect subclinical levels of inflammation. Soluble …
interest in numerous biomarkers that detect subclinical levels of inflammation. Soluble …
Inflammatory markers and cardiometabolic diseases
Objectives: A growing body of evidence emerges that obesity, metabolic syndrome, type 2
diabetes and cardiovascular disease are intimately related to chronic inflammation …
diabetes and cardiovascular disease are intimately related to chronic inflammation …
Management of endocrine disease: diabetes and osteoporosis: cause for concern?
J Starup-Linde, P Vestergaard - European Journal of …, 2015 - academic.oup.com
Diabetes and osteoporosis are both frequent conditions, and they may thus occur
simultaneously by chance. However, a growing body of evidence suggests that …
simultaneously by chance. However, a growing body of evidence suggests that …
The paradoxical role of IL-17 in atherosclerosis
F Gong, Z Liu, J Liu, P Zhou, Y Liu, X Lu - Cellular immunology, 2015 - Elsevier
Atherosclerosis is a chronic inflammatory disease mediated by innate and adaptive immune
responses. In recent years, CD4+ T cells (Th1, Th2, Treg, and Th17) have been increasingly …
responses. In recent years, CD4+ T cells (Th1, Th2, Treg, and Th17) have been increasingly …