Markers of inflammation associated with plaque progression and instability in patients with carotid atherosclerosis

E Ammirati, F Moroni, GD Norata… - Mediators of …, 2015 - Wiley Online Library
Atherosclerosis is the focal expression of a systemic disease affecting medium‐and large‐
sized arteries, in which traditional cardiovascular risk factor and immune factors play a key …

Novel anti-inflammatory therapies for the treatment of atherosclerosis

R Khan, V Spagnoli, JC Tardif, PL L'Allier - Atherosclerosis, 2015 - Elsevier
The underlying role of inflammation in atherosclerosis has been characterized. However,
current treatment of coronary artery disease (CAD) predominantly consists of targeted …

Proof that lower is better—LDL cholesterol and IMPROVE-IT

JA Jarcho, JF Keaney Jr - New England Journal of Medicine, 2015 - Mass Medical Soc
The so-called LDL hypothesis is the concept that excess low-density lipoprotein (LDL)
cholesterol is a causal factor in the development of atherosclerotic vascular disease. By …

Cardiovascular risk assessment: a global perspective

D Zhao, J Liu, W Xie, Y Qi - Nature Reviews Cardiology, 2015 - nature.com
An important strategy in primary prevention of cardiovascular diseases (CVD) is the early
identification of high-risk individuals. Effective implementation of a strategy to identify these …

Reverse epidemiology of traditional cardiovascular risk factors in the geriatric population

SF Ahmadi, E Streja, G Zahmatkesh, D Streja… - Journal of the American …, 2015 - Elsevier
Traditional risk factors of cardiovascular death in the general population, including body
mass index (BMI), serum cholesterol, and blood pressure (BP), are also found to relate to …

Statin use and exacerbations in individuals with chronic obstructive pulmonary disease

TS Ingebrigtsen, JL Marott, BG Nordestgaard, P Lange… - Thorax, 2015 - thorax.bmj.com
Background We tested the hypothesis that statin use in individuals with COPD is associated
with a reduced risk of exacerbations. Methods We identified 5794 individuals with COPD …

suPAR: a new biomarker for cardiovascular disease?

GW Hodges, CN Bang, K Wachtell… - Canadian Journal of …, 2015 - Elsevier
The fundamental role of inflammation in cardiovascular disease (CVD) has prompted
interest in numerous biomarkers that detect subclinical levels of inflammation. Soluble …

Inflammatory markers and cardiometabolic diseases

N Esser, N Paquot, AJ Scheen - Acta Clinica Belgica, 2015 - Taylor & Francis
Objectives: A growing body of evidence emerges that obesity, metabolic syndrome, type 2
diabetes and cardiovascular disease are intimately related to chronic inflammation …

Management of endocrine disease: diabetes and osteoporosis: cause for concern?

J Starup-Linde, P Vestergaard - European Journal of …, 2015 - academic.oup.com
Diabetes and osteoporosis are both frequent conditions, and they may thus occur
simultaneously by chance. However, a growing body of evidence suggests that …

The paradoxical role of IL-17 in atherosclerosis

F Gong, Z Liu, J Liu, P Zhou, Y Liu, X Lu - Cellular immunology, 2015 - Elsevier
Atherosclerosis is a chronic inflammatory disease mediated by innate and adaptive immune
responses. In recent years, CD4+ T cells (Th1, Th2, Treg, and Th17) have been increasingly …