Altered cytotoxicity of ROS-inducing compounds by sodium pyruvate in cell culture medium depends on the location of ROS generation

JL Kelts, JJ Cali, SJ Duellman, J Shultz - Springerplus, 2015 - Springer
Induction of oxidative stress by drugs and other xenobiotics is an important mechanism of
cytotoxicity. However, in vitro studies on the relationship between oxidative stress and …

KdmA, a histone H3 demethylase with bipartite function, differentially regulates primary and secondary metabolism in Aspergillus nidulans

A Gacek‐Matthews, LM Noble, C Gruber… - Molecular …, 2015 - Wiley Online Library
A spergillus nidulans kdmA encodes a member of the KDM 4 family of jumonji histone
demethylase proteins, highly similar to metazoan orthologues both within functional …

Incubator-independent cell-culture perfusion platform for continuous long-term microelectrode array electrophysiology and time-lapse imaging

D Saalfrank, AK Konduri, S Latifi… - Royal Society …, 2015 - royalsocietypublishing.org
Most in vitro electrophysiology studies extract information and draw conclusions from
representative, temporally limited snapshot experiments. This approach bears the risk of …

On the effect of serum on the transport of reactive oxygen species across phospholipid membranes

EJ Szili, SH Hong, RD Short - Biointerphases, 2015 - pubs.aip.org
The transport of plasma generated reactive oxygen species (ROS) across a simple
phospholipid membrane mimic of a (real) cell was investigated. Experiments were …

Visible light and near-infrared-responsive chromophores for drug delivery-on-demand applications

CS Linsley, VY Quach, G Agrawal, E Hartnett… - Drug delivery and …, 2015 - Springer
The need for temporal-spatial control over the release of biologically active molecules has
motivated efforts to engineer novel drug delivery-on-demand strategies actuated via light …

Controlled intracellular generation of reactive oxygen species in human mesenchymal stem cells using porphyrin conjugated nanoparticles

AS Lavado, VM Chauhan, AA Zen, F Giuntini… - Nanoscale, 2015 - pubs.rsc.org
Nanoparticles capable of generating controlled amounts of intracellular reactive oxygen
species (ROS), that advance the study of oxidative stress and cellular communication, were …

Noninvasive oxygen monitoring in three-dimensional tissue cultures under static and dynamic culture conditions

B Weyand, M Nöhre, E Schmälzlin, M Stolz… - BioResearch open …, 2015 - liebertpub.com
We present a new method for noninvasive real-time oxygen measurement inside three-
dimensional tissue-engineered cell constructs in static and dynamic culture settings in a …

[PDF][PDF] Amending in vitro culture condition to overcome oxidative stress in assisted reproduction techniques (ART)

S Zavareh, A Talebi… - Archives of Advances in …, 2015 - journals.sbmu.ac.ir
In assisted reproduction techniques (ART) settings, reactive oxygen species (ROS) can be
produced from endogenous and exogenous sources during in vitro manipulation …

Reactive oxygen species and cytotoxicity in rainbow trout hepatocytes: effects of medium and incubation time

M Yazdani, RE Paulsen, T Gjøen, K Hylland - Bulletin of environmental …, 2015 - Springer
This study evaluated the effects of exposure medium and culture age on intracellular
reactive oxygen species (ROS) development and cytotoxicity in fish hepatocytes following …

UV-induced signaling: role of reactive oxygen species

LO Klotz - Studies on Experimental Toxicology and …, 2015 - Springer
Ultraviolet radiation causes the generation of reactive oxygen species (ROS) in mammalian
cells and tissues, followed by ROS-dependent signaling processes. These signaling …