The role of reactive oxygen species in myelofibrosis and related neoplasms

ME Bjørn, HC Hasselbalch - Mediators of Inflammation, 2015 - Wiley Online Library
Reactive oxygen species (ROS) have been implicated in a wide variety of disorders ranging
between traumatic, infectious, inflammatory, and malignant diseases. ROS are involved in …

[HTML][HTML] Hematopoietic cell transplantation as curative therapy for patients with myelofibrosis: long-term success in all age groups

HJ Deeg, C Bredeson, S Farnia, K Ballen… - Biology of Blood and …, 2015 - Elsevier
Myeloproliferative neoplasms (MPN) are chronic marrow disorders with variable prognoses.
Most patients with polycythemia vera, essential thrombocythemia, or even primary …

[HTML][HTML] An International MDS/MPN Working Group's perspective and recommendations on molecular pathogenesis, diagnosis and clinical characterization of …

TI Mughal, NCP Cross, E Padron, RV Tiu… - …, 2015 - ncbi.nlm.nih.gov
In the 2008 WHO classification, chronic myeloid malignancies that share both
myelodysplastic and myeloproliferative features define the myelodysplastic …

Therapeutic benefit of decitabine, a hypomethylating agent, in patients with high-risk primary myelofibrosis and myeloproliferative neoplasm in accelerated or blastic …

T Badar, HM Kantarjian, F Ravandi, E Jabbour… - Leukemia research, 2015 - Elsevier
Myeloproliferative neoplasm (MPN) transformed to acute myeloid leukemia (MPN-AML),
MPN in accelerated phase (MPN-AP), and high-risk primary myelofibrosis (PMF) are …

Blast transformation in chronic myelomonocytic leukemia: risk factors, genetic features, survival, and treatment outcome

MM Patnaik, EA Wassie, TL Lasho… - American journal of …, 2015 - Wiley Online Library
Among 274 patients with chronic myelomonocytic leukemia (CMML) and followed for a
median of 17.1 months, blast transformation (BT) occurred in 36 (13%). On multivariable …

Clonal evolution revealed by whole genome sequencing in a case of primary myelofibrosis transformed to secondary acute myeloid leukemia

EK Engle, DAC Fisher, CA Miller, MD McLellan… - Leukemia, 2015 - nature.com
Clonal architecture in myeloproliferative neoplasms (MPNs) is poorly understood. Here we
report genomic analyses of a patient with primary myelofibrosis (PMF) transformed to …

Azacytidine for the treatment of retrospective analysis from the Gruppo Laziale for the study of Ph-negative MPN

A Andriani, M Montanaro, MT Voso, N Villivà… - Leukemia research, 2015 - Elsevier
To highlight the role of azacytidine (AZA) in patients with myeloproliferative neoplasms
developing blast phase (MPN-BP), we evaluated retrospectively 19 patients [M/F 15/4 …

Acute myeloid leukemia and other types of disease progression in myeloproliferative neoplasms

M Czader, A Orazi - American journal of clinical pathology, 2015 - academic.oup.com
Objectives: This session of the Society for Hematopathology/European Association for
Haematopathology workshop focused on disease progression in myeloproliferative …

Secondary acute myeloid leukemias arising from Philadelphia chromosome negative myeloproliferative neoplasms: pathogenesis, risk factors, and therapeutic …

M Tallarico, O Odenike - Current hematologic malignancy reports, 2015 - Springer
The classic Philadelphia chromosome negative myeloproliferative neoplasms including
primary myelofibrosis, polycythemia vera, and essential thrombocythemia are associated …

Survival of patients with chronic myeloproliferative neoplasms and new primary cancers: a population-based cohort study

H Frederiksen, DK Farkas, CF Christiansen… - The Lancet …, 2015 - thelancet.com
Background Patients with chronic myeloproliferative neoplasms are at increased risk of new
solid or haematological cancers, but how prognosis is affected in patients with preceding …